Ovarian carcinoma pathology and genetics: recent advances

被引：157
作者：
Gilks, C. Blake [1 ,2 ]
Prat, Jaime [3 ]
机构：
[1] Vancouver Gen Hosp, Dept Pathol, Vancouver, BC V5Z 1M9, Canada
[2] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
[3] Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, Dept Pathol, E-08193 Barcelona, Spain
来源：
HUMAN PATHOLOGY | 2009年 / 40卷 / 09期
关键词：
Ovarian cancer; Ovarian surface epithelial carcinoma; Tumor cell type; Serous; Clear cell; Endometrioid; Mucinous; CLEAR-CELL CARCINOMA; GRADE SEROUS CARCINOMA; CORD-STROMAL TUMORS; DISTINCT-HISTOLOGIC-TYPE; DNA-REPAIR DEFECT; BRCA MUTANT-CELLS; MUCINOUS TUMORS; ENDOMETRIOID CARCINOMAS; BORDERLINE TUMORS; CLINICOPATHOLOGICAL ANALYSIS;
D O I：
10.1016/j.humpath.2009.04.017
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
In this review we summarize recent advances in the histopathological diagnostic criteria and molecular pathology of the main subtypes of ovarian Surface epithelial carcinoma. These advances have greatly improved our understanding of the biology of ovarian carcinoma and are also relevant to patient management. With progress toward subtype-specific treatment of ovarian carcinoma, accurate, reproducible histopathological diagnosis of these subtypes by practicing pathologists is increasingly important. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码：1213 / 1223
页数：11
相关论文
共 94 条
[91]   Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer [J].
Tutt, A. N. J. ;
Lord, C. J. ;
McCabe, N. ;
Farmer, H. ;
Turner, N. ;
Martin, N. M. ;
Jackson, S. P. ;
Smith, G. C. M. ;
Ashworth, A. .
MOLECULAR APPROACHES TO CONTROLLING CANCER, 2005, 70 :139-148
[92]   Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7 [J].
Vang, Russell ;
Gown, Allen M. ;
Wu, Lee-Shu-Fune ;
Barry, Todd S. ;
T Wheeler, Darren ;
Yemelyanova, Anna ;
Seidman, Jeffrey D. ;
Ronnett, Brigitte M. .
MODERN PATHOLOGY, 2006, 19 (11) :1421-1428
[93]   Prognostic factors for stage III epithelial ovarian cancer: A Gynecologic Oncology Group Study [J].
Winter, William E., III ;
Maxwell, G. Larry ;
Tian, Chunqiao ;
Carlson, Jay W. ;
Ozols, Robert F. ;
Rose, Peter G. ;
Markman, Maurie ;
Armstrong, Deborah K. ;
Muggia, Franco ;
McGuire, William P. .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (24) :3621-3627
[94]   OVARIAN ENDOMETRIOID CARCINOMAS RESEMBLING SEX CORD STROMAL TUMORS - A CLINICOPATHOLOGICAL ANALYSIS OF 13 CASES [J].
YOUNG, RH ;
PRAT, J ;
SCULLY, RE .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1982, 6 (06) :513-522
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