Ovarian carcinoma pathology and genetics: recent advances

被引:157
作者
Gilks, C. Blake [1 ,2 ]
Prat, Jaime [3 ]
机构
[1] Vancouver Gen Hosp, Dept Pathol, Vancouver, BC V5Z 1M9, Canada
[2] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
[3] Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, Dept Pathol, E-08193 Barcelona, Spain
关键词
Ovarian cancer; Ovarian surface epithelial carcinoma; Tumor cell type; Serous; Clear cell; Endometrioid; Mucinous; CLEAR-CELL CARCINOMA; GRADE SEROUS CARCINOMA; CORD-STROMAL TUMORS; DISTINCT-HISTOLOGIC-TYPE; DNA-REPAIR DEFECT; BRCA MUTANT-CELLS; MUCINOUS TUMORS; ENDOMETRIOID CARCINOMAS; BORDERLINE TUMORS; CLINICOPATHOLOGICAL ANALYSIS;
D O I
10.1016/j.humpath.2009.04.017
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
In this review we summarize recent advances in the histopathological diagnostic criteria and molecular pathology of the main subtypes of ovarian Surface epithelial carcinoma. These advances have greatly improved our understanding of the biology of ovarian carcinoma and are also relevant to patient management. With progress toward subtype-specific treatment of ovarian carcinoma, accurate, reproducible histopathological diagnosis of these subtypes by practicing pathologists is increasingly important. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:1213 / 1223
页数:11
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