Immobilization of glyoxylic acid on Wang resin

被引：18

作者：

Schlienger, N

Bryce, MR

Hansen, TK

机构：

[1] Novo Nordisk AS, Med Chem Res 4, DK-2760 Maaloev, Denmark

[2] Univ Durham, Dept Chem, Durham DH1 3LE, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 26期

关键词：

aldehydes; solid-phase synthesis;

D O I：

10.1016/S0040-4039(00)00799-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report herein the simple preparation of immobilized glyoxylic acid, where the acid function is either linked through an amide or an ester bond to Wang resin. These compounds represent interesting aldehyde inputs for the generation of new libraries of small molecules. (C) 2000 Elsevier Science Ltd. All rights reserved.

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收藏

页码：5147 / 5150

页数：4

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