Correlation Between In Vivo Reflectance Confocal Microscopy and Horizontal Histopathology in Skin Cancer: A Review

被引：13
作者：
Broggi, Giuseppe [1 ]
Verzi, Anna Elisa [2 ]
Caltabiano, Rosario [1 ]
Micali, Giuseppe [2 ]
Lacarrubba, Francesco [2 ]
机构：
[1] Univ Catania, Dept Med Surg Sci & Adv Technol GF Ingrassia, Anat Pathol, Catania, Italy
[2] Univ Catania, Dermatol Clin, Catania, Italy
来源：
FRONTIERS IN ONCOLOGY | 2021年 / 11卷
关键词：
horizontal histopathology; reflectance confocal microscopy; skin cancer; correlation; horizontal histopathological sections;
D O I：
10.3389/fonc.2021.653140
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In dermatopathological daily practice, vertical histopathology sections are classically used to analyze skin biopsies. Conversely, horizontal histopathological sections are currently used for the diagnosis of some types of alopecia. In the last years the morphological findings obtained by horizontal histopathology have been correlated to those obtained by in vivo reflectance confocal microscopy which provides the same "point of view" of the skin. This review paper emphasizes the strong matching and correlation between reflectance confocal microscopy images and horizontal histopathology in cutaneous neoplasms, further demonstrating the strong reliability of this innovative, non-invasive technique in the management of skin tumors.
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页数：7
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