Synthesis of 3-tert-Butyl-7,8-nitro(dinitro)pyrazolo-[5,1-c][1,2,4]triazin-4(6H)-ones

被引：2

作者：

Ivanov, S. M. ^{[1
]}

机构：

[1] Russian Acad Sci, Zelinskii Inst Organ Chem, Moscow 119991, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 57卷 / 02期

关键词：

pyrazolo[5; 1-c][1; 2; 4]triazine; 1; 4-triazine; diazotization; decarboxylation; nitration;

D O I：

10.1134/S1070428021020032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-tert-Butyl-8-nitro-7-R-pyrazolo[5,1-c][1,2,4]triazin-4(6H)-ones (R = H, Cl, Br, NO2, N-3) were prepared by nitration with HNO3/H2SO4 of the corresponding 7-R-substituted 8-carboxylic acids or their analogs with a vacant C-8 position. The latter were synthesized by diazotization of 7-amino-3-tert-butyl-4-oxo-4,6-dihydropyrazolo[5,1-c][1,2,4]triazin-8-carboxylic acid. The electrophilic halogenation and cycloaddition of the 7-azido and 7-nitro derivatives of the synthesized compounds were considered. The structures of the products were confirmed by IR, heteronuclear NMR spectroscopy, HRMS, and single-crystal XRD.

引用

页码：151 / 159

页数：9

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