Rapid detection of Mycobacterium tuberculosis in sputum by Patho-TB kit in comparison with direct microscopy and culture

被引：12

作者：

Ben-Selma, Walid ^{[1
]}

Ben-Kahla, Imen ^{[1
]}

Marzouk, Manel ^{[1
]}

Ferjeni, Asma ^{[1
]}

Ghezal, Samira ^{[1
]}

Ben-Said, Moncef ^{[1
]}

Boukadida, Jalel ^{[1
]}

机构：

[1] CHU Farhat Hached, Microbiol & Immunol Lab UR02SP13, Sousse 4000, Tunisia

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2009年 / 65卷 / 03期

关键词：

Diagnosis; Mycobacterial antigens; Mycobacterium tuberculosis; Tuberculosis; PULMONARY TUBERCULOSIS; DIAGNOSIS; ANTIGENS; TRANSPORTATION; RECOMBINATION; TRANSMISSION; MENINGITIS; ASSAY;

D O I：

10.1016/j.diagmicrobio.2009.07.021

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The usefulness of a new rapid diagnostic test (Patho-TB) using antibodies specific to mycobacterial antigens was evaluated for the rapid discrimination between pulmonary tuberculosis (TB) and non-TB pulmonary diseases on sputa. One hundred Sputa collected from 79 active TB patients and from 21 patients with non-TB pulmonary diseases (asthma and chronic obstructive pulmonary disease) were enrolled into the study and tested for the presence of Mycobacterium tuberculosis by Ziehl-Neelsen smear, Patho-TB kit, and Lowenstein-Jensen culture. The sensitivity, specificity, positive predictive value, and negative predictive value of the Patho-TB test were 95%, 100%, 100%, and 84%, respectively. Patho-TB test is simple, quick, and easy to perforin. Its sensitivity, specificity, and positive predictive Value are satisfactory. Therefore, it could be used as a screening test in poorly equipped laboratories of TB endemic areas. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：232 / 235

页数：4

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