Cardiac complications in pediatric patients on the ketogenic diet

被引：116
|
作者：
Best, TH
Franz, DN
Gilbert, DL
Nelson, DP
Epstein, MR
机构：
[1] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH 45221 USA
[2] Univ Cincinnati, Coll Med, Dept Cardiol, Cincinnati, OH 45221 USA
[3] Univ Cincinnati, Coll Med, Dept Neurol, Cincinnati, OH 45221 USA
来源：
NEUROLOGY | 2000年 / 54卷 / 12期
关键词：
cardiac complications; pediatric patients; ketogenic diet;
D O I：
10.1212/WNL.54.12.2328
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Cardiac complications of the ketogenic diet, in the absence of selenium deficiency, have not been reported. Twenty patients on the ketogenic diet at one institution were investigated. Prolonged QT interval (QTc) was found in 3 patients (15%). There was a significant correlation between prolonged QTc and both low serum bicarbonate and high beta-hydroxybutyrate. In addition, three patients had evidence of cardiac chamber enlargement. One patient with severe dilated cardiomyopathy and prolonged QTc normalized when the diet was discontinued.
引用
收藏
页码：2328 / 2330
页数：3
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