COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality

被引：1
|
作者：
Benbassat, Jochanan [1 ,5 ]
Froom, Paul [2 ,3 ]
Shimoni, Zvi [4 ]
机构：
[1] Hadassah Univ Hosp Jerusalem, Dept Med, Jerusalem, Israel
[2] Laniado Hosp, Sanz Med Ctr, Clin Util Dept, Netanya, Israel
[3] Tel Aviv Univ, Sch Publ Hlth, Tel Aviv, Israel
[4] Laniado Hosp, Sanz Med Ctr, Netanya, Israel
[5] POB 3894, IL-91037 Jerusalem, Israel
来源：
PREVENTIVE MEDICINE | 2022年 / 164卷
关键词：
COVID-19; vaccination; Mortality; Efficacy of vaccine; Healthy adherer effect; Retrospective cohort studies; Israel; UNITED-STATES; ADHERENCE; RISK;
D O I：
10.1016/j.ypmed.2022.107326
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
We retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65-2.44) (unadjusted) and 1.61 (1.29-2.03) after adjustment for the independent variables. This "healthy adherer effect" may confound observational assessments of the clinical efficacy of COVID-19 vaccines.
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页数：3
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