A diterpene quinone from the bark of Cryptomeria japonica

被引：50
作者：
Kofujita, H
Ota, M
Takahashi, K
Kawai, Y
Hayashi, Y
机构：
[1] Iwate Univ, Fac Agr, Morioka, Iwate 0208550, Japan
[2] Yamagata Univ, Fac Agr, Tsuruoka 9978555, Japan
[3] Kyoto Univ, Chem Res Inst, Uji, Kyoto 6110011, Japan
[4] Tamanoi Vinegar Co, Tamanoi Res Ctr, Koriyama 6391038, Japan
来源：
PHYTOCHEMISTRY | 2002年 / 61卷 / 08期
关键词：
Cryptomeria japonica; abietane; diterpene; quinone; antifungal activity; cytotoxic activity;
D O I：
10.1016/S0031-9422(02)00352-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A diterpene, cryptoquinone, was isolated from the bark of Cryptomeria japonica, the structure, 7,11,14-trioxoabieta-8,12-diene, was established by spectral analyses and X-ray crystallography. This diterpene quinone showed moderate antifungal activities against Pyricularia orizae and Alternaria alternata, and cytotoxic activity against mouse lymphoid neoplasm (P388) cells with an IC50 of 0.26 mug/ml. (C) 2002 Elsevier Science Ltd. All rights reserved.
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收藏
页码：895 / 898
页数：4
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