An exonic polymorphism in the human glucose phosphate isomerase (GPI) gene

被引：3
|
作者：
Xu, WM [1 ]
Beutler, E [1 ]
机构：
[1] Scripps Res Inst, DEPT MOL & EXPT MED, LA JOLLA, CA 92037 USA
来源：
BLOOD CELLS MOLECULES AND DISEASES | 1997年 / 23卷 / 18期
关键词：
Asian; Jewish; White American; restriction site;
D O I：
10.1006/bcmd.1997.0154
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A polymorphic site has been found in the human glucose phosphate isomerase (GPI) gene. This site is produced by a A-->G substitution at nt 489 of GPI cDNA, resulting in a silent mutation. To our knowledge, it is the first defined polymorphism in the gene. It is present with similar gene frequencies in Asian, American White, African American, and Jewish populations.
引用
收藏
页码：377 / 379
页数：3
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