Metal Species-Encapsulated Mesoporous Silica Nanoparticles: Current Advancements and Latest Breakthroughs

被引：137

作者：

Kankala, Ranjith Kumar ^{[1
]}

Zhang, Hongbo ^{[2
,3
]}

Liu, Chen-Guang ^{[1
]}

Kanubaddi, Kiran Reddy ^{[4
,5
]}

Lee, Chia-Hung ^{[4
,5
]}

Wang, Shi-Bin ^{[1
]}

Cui, Wenguo ^{[2
]}

Santos, Helder A. ^{[6
,7
]}

Lin, KaiLi ^{[8
]}

Chen, Ai-Zheng ^{[1
]}

机构：

[1] Huaqiao Univ, Fujian Prov Key Lab Biochem Technol, Inst Biomat & Tissue Engn, Coll Chem Engn, Xiamen 361021, Fujian, Peoples R China

[2] Shanghai Jiao Tong Univ, Shanghai Key Lab Prevent & Treatment Bone & Joint, Shanghai Inst Traumatol & Orthopaed, Ruijin Hosp,Sch Med, 197 Ruijin 2nd Rd, Shanghai 200025, Peoples R China

[3] Abo Akad Univ, Dept Pharmaceut Sci Lab, FL-00520 Helsinki, Finland

[4] Natl Dong Hwa Univ, Dept Life Sci, Hualien 97401, Taiwan

[5] Natl Dong Hwa Univ, Inst Biotechnol, Hualien 97401, Taiwan

[6] Univ Helsinki, Fac Pharm, Div Pharmaceut Chem & Technol, Drug Res Program, FI-00014 Helsinki, Finland

[7] Univ Helsinki, Helsinki Inst Life Sci HiLIFE, FI-00014 Helsinki, Finland

[8] Shanghai Jiao Tong Univ, Dept Oral & Craniomaxillofacial Surg, Shanghai Res Inst Stomatol,Sch Med, Shanghai Key Lab Stomatol,Shanghai Peoples Hosp 9, Shanghai 200011, Peoples R China

来源：

ADVANCED FUNCTIONAL MATERIALS | 2019年 / 29卷 / 43期

基金：

中国国家自然科学基金; 欧洲研究理事会;

关键词：

biomedical field; catalysis; controlled drug delivery; mesoporous silica nanoparticles; metal nanoparticles; CATALYZED PROPYLENE EPOXIDATION; RESPONSIVE CONTROLLED-RELEASE; ION-EXCHANGE METHOD; OVERCOMING MULTIDRUG-RESISTANCE; PALLADIUM BIPYRIDYL COMPLEX; H BOND OXIDATION; DRUG-DELIVERY; FACILE SYNTHESIS; INORGANIC NANOPARTICLES; HYDROTHERMAL STABILITY;

D O I：

10.1002/adfm.201902652

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Despite their advantageous morphological attributes and attractive physicochemical properties, mesoporous silica nanoparticles (MSNs) are merely supported as carriers or vectors for a reason. Incorporating various metal species in the confined nanospaces of MSNs (M-MSNs) significantly enriches their mesoporous architecture and diverse functionalities, bringing exciting potentials to this burgeoning field of research. These incorporated guest species offer enormous benefits to the MSN hosts concerning the reduction of their eventual size and the enhancement of their performance and stability, among other benefits. Substantially, the guest species act through contributing to reduced aggregation, augmented durability, ease of long-term storage, and reduced toxicity, attributes that are of particular interest in diverse fields of biomedicine. In this review, the first aim is to discuss the current advancements and latest breakthroughs in the fabrication of M-MSNs, emphasizing the pros and cons, the confinement of various metal species in the nanospaces of MSNs, and various factors influencing the encapsulation of metal species in MSNs. Further, an emphasis on potential applications of M-MSNs in various fields, including in adsorption, catalysis, photoluminescence, and biomedicine, among others, along with a set of examples is provided. Finally, the advances in M-MSNs with perspectives are summarized.

引用

页数：42

共 304 条

[1] Asymmetric Silica Nanoparticles with Tunable Head-Tail Structures Enhance Hemocompatibility and Maturation of Immune Cells [J].