Tackling type 2 diabetes-associated cardiovascular and renal comorbidities: a key challenge for drug development

被引：12
作者：
Adeghate, Ernest A. [1 ]
Kalasz, Huba [2 ]
Al Jaberi, Saeeda [1 ]
Adeghate, Jennifer [3 ]
Tekes, Kornelia [4 ]
机构：
[1] United Arab Emirates Univ, Coll Med & Hlth Sci, Dept Anat, Al Ain, U Arab Emirates
[2] Semmelweis Univ, Fac Med, Dept Pharmacol & Pharmacotherapy, Budapest, Hungary
[3] Univ Pittsburgh, Sch Med, Dept Ophthalmol, Pittsburgh, PA 15261 USA
[4] Semmelweis Univ, Dept Pharmacodynam, Fac Pharm, Budapest, Hungary
来源：
EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2021年 / 30卷 / 02期
关键词：
Type 2 Diabetes mellitus; cardiovascular diseases; renal diseases; pharmacotherapy; T2DM comorbidities; hypoglycemic agents; IMPAIRED GLUCOSE-TOLERANCE; CHRONIC KIDNEY-DISEASE; MYOCARDIAL-INFARCTION; FOLLOW-UP; RISK; OUTCOMES; MELLITUS; ACARBOSE; SULFONYLUREAS; EPIDEMIOLOGY;
D O I：
10.1080/13543784.2021.1865914
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：85 / 93
页数：9
相关论文
共 77 条
[1]   Antidiabetic Agents in Patients with Chronic Kidney Disease and End-Stage Renal Disease on Dialysis: Metabolism and Clinical Practice [J].
Abe, Masanori ;
Okada, Kazuyoshi ;
Soma, Masayoshi .
CURRENT DRUG METABOLISM, 2011, 12 (01) :57-69
[2]   Nonalcoholic Fatty Liver Disease Increases Risk of Death Among Patients With Diabetes: A Community-Based Cohort Study [J].
Adams, Leon A. ;
Harmsen, Scott ;
St Sauver, Jennifer L. ;
Charatcharoenwitthaya, Phunchai ;
Enders, Felicity B. ;
Therneau, Terry ;
Angulo, Paul .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (07) :1567-1573
[3]   Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: A short review [J].
Adeghate, E .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2004, 261 (1-2) :187-191
[4]   Medicinal Chemistry of Drugs Used in Diabetic Cardiomyopathy [J].
Adeghate, E. ;
Kalasz, H. ;
Veress, G. ;
Tekes, K. .
CURRENT MEDICINAL CHEMISTRY, 2010, 17 (06) :517-551
[5]   An update on the etiology and epidemiology of diabetes mellitus [J].
Adeghate, Ernest ;
Schattner, Peter ;
Dunn, Earl .
DIABETES MELLITUS AND ITS COMPLICATIONS: MOLECULAR MECHANISMS, EPIDEMIOLOGY, AND CLINICAL MEDICINE, 2006, 1084 :1-29
[6]   An update of SGLT1 and SGLT2 inhibitors in early phase diabetes-type 2 clinical trials [J].
Adeghate, Ernest ;
Mohsin, Sahar ;
Adi, Faisal ;
Ahmed, Fares ;
Yahya, Ali ;
Kalasz, Huba ;
Tekes, Kornelia ;
Adeghate, Ernest A. .
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019, 28 (09) :811-820
[7]   Prevalence of the Metabolic Syndrome in the United States, 2003-2012 [J].
Aguilar, Maria ;
Bhuket, Taft ;
Torres, Sharon ;
Liu, Benny ;
Wong, Robert J. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2015, 313 (19) :1973-1974
[8]   Diabetic Kidney Disease Challenges, Progress, and Possibilities [J].
Alicic, Radica Z. ;
Rooney, Michele T. ;
Tuttle, Katherine R. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017, 12 (12) :2032-2045
[9]  
[Anonymous], 2013, CANC DISCOV
[10]  
Azimova K, 2014, OCHSNER J, V14, P616
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