Enantioselective synthesis of (-)-lasubine II

被引：19

作者：

Chandrasekhar, S. ^{[1
]}

Murali, R. V. N. S. ^{[1
]}

Reddy, Ch. Raji ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Div 1, Hyderabad 500607, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 40期

关键词：

Alkaloid; Lasubine; Organocatalysis; Mannich reaction; Aza-Michael addition; Maruoka allylation; ASYMMETRIC ALDOL REACTIONS; AMINO BETA-KETOESTERS; QUINOLIZIDINE ALKALOIDS; LASUBINE-II; L-PROLINE; INTRAMOLECULAR ACYLATION; CONJUGATE ADDITION; MANNICH REACTIONS; MICHAEL; CONCISE;

D O I：

10.1016/j.tetlet.2009.07.128

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly enantioselective synthesis of lythraceae alkaloid lasubine II has been achieved using organo-catalyzed Mannich reaction. Maruoka allylation, and aza-Michael addition as the key steps. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：5686 / 5688

页数：3

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