IDENTIFICATION OF A NOVEL H3.3.K27M MUTATION-DERIVED NEOANTIGEN EPITOPE AND CLONING OF H3.3.K27M-SPECIFIC T-CELL RECEPTOR FOR T-CELL THERAPY IN GLIOMAS

被引：0
|
作者：
Chheda, Z. [1 ]
Kohanbash, G. [1 ]
Sidney, J. [2 ]
Okada, K. [1 ]
Jahan, N. [1 ]
Mueller, S. [1 ]
Sette, A. [2 ]
Hou, Y. [1 ]
Okada, H. [1 ]
机构：
[1] Univ Calif San Francisco, San Francisco, CA 94143 USA
[2] La Jolla Inst Allergy & Immunol, La Jolla, CA USA
来源：
NEURO-ONCOLOGY | 2017年 / 19卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OS09.4
引用
收藏
页码：18 / 19
页数：3
相关论文
共 50 条
  • [1] IDENTIFICATION OF A NOVEL H3.3.K27M MUTATION-DERIVED NEOANTIGEN EPITOPE AND CLONING OF A SPECIFIC T-CELL RECEPTOR FOR T-CELL THERAPY IN GLIOMAS
    Kohanbash, Gary
    Chheda, Zinal
    Sidney, John
    Okada, Kaori
    Shrivastav, Shruti
    Carrera, Diego
    Liu, Shuming
    Jahan, Naznin
    Mueller, Sabine
    Pollack, Ian
    Carcaboso, Angel
    Sette, Alessandro
    Hou, Yafei
    Okada, Hideho
    NEURO-ONCOLOGY, 2016, 18 : 87 - 87
  • [2] Identification of a novel and a shared H3.3K27M mutation derived neoantigen epitope and H3.3K27M specific TCR engineered T cell therapy for glioma
    Chheda, Zinal
    Kohanbash, Gary
    Sidney, John
    Okada, Kaori
    Jahan, Naznin
    Carrera, Diego
    Watchmaker, Payal
    Downey, Kira
    Liu, Shuming
    Shrivastav, Shruti
    Mueller, Sabine
    Pollack, Ian F.
    Carcaboso, Angel M.
    Sette, Alessandro
    Hou, Yafei
    Okada, Hideho
    CANCER RESEARCH, 2017, 77
  • [3] H3.3K27M MUTATION-DERIVED NOVEL NEOANTIGEN - CHARACTERIZATION OF THE HLA-A2-BINDING EPITOPE AND A SPECIFIC T CELL RECEPTOR FOR DEVELOPMENT OF T CELL-BASED IMMUNOTHERAPY
    Chheda, Zinal
    Kohanbash, Gary
    Okada, Kaori
    Jahan, Naznin
    Sidney, John
    Pecoraro, Matteo
    Carrera, Diego
    Shrivastav, Shruti
    Liu, Shuming
    Downey, Kira
    Chuntova, Pavlina
    Watchmaker, Payal
    Mueller, Sabine
    Pollack, Ian
    Rajalingam, Raja
    Montero Carcaboso, Angel
    Mann, Matthias
    Sette, Alessandro
    Hou, Yafei
    Okada, Hideho
    NEURO-ONCOLOGY, 2017, 19 : 121 - 121
  • [4] H3.3K27M mutation-derived novel neoantigen - characterization of the HLA-A2-binding epitope and a specific T cell receptor for development of T cell-based immunotherapy
    Chheda, Zinal
    Kohanbash, Gary
    Okada, Kaori
    Jahan, Naznin
    Sidney, John
    Pecoraro, Matteo
    Carrera, Diego
    Shrivastav, Shruti
    Liu, Shuming
    Mueller, Sabine
    Pollack, Ian
    Rajalingam, Raja
    Carcaboso, Angel
    Mann, Matthias
    Sette, Alessandro
    Hou, Yafei
    Okada, Hideho
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2017, 5
  • [5] Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy
    Chheda, Zinal S.
    Kohanbash, Gary
    Okada, Kaori
    Jahan, Naznin
    Sidney, John
    Pecoraro, Matteo
    Yang, Xinbo
    Carrera, Diego A.
    Downey, Kira M.
    Shrivastav, Shruti
    Liu, Shuming
    Lin, Yi
    Lagisetti, Chetana
    Chuntova, Pavlina
    Watchmaker, Payal B.
    Mueller, Sabine
    Pollack, Ian F.
    Rajalingam, Raja
    Carcaboso, Angel M.
    Mann, Matthias
    Sette, Alessandro
    Garcia, K. Christopher
    Hou, Yafei
    Okada, Hideho
    JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 215 (01): : 141 - 157
  • [6] Novel and shared neoantigen for glioma T cell therapy derived from histone 3 variant H3.3 K27M mutation
    Hou, Yafei
    Kohanbash, Gary
    Okada, Kaori
    Shrivastav, Shruti
    Smith-Cohn, Matthew
    Nicolaides, Theodore
    Mueller, Sabine
    Carcaboso, Angel Montero
    Pollack, Ian F.
    Okada, Hideho
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (01)
  • [7] NOVEL AND SHARED NEOANTIGEN FOR GLIOMA T CELL THERAPY DERIVED FROM HISTONE 3 VARIANT H3.3 K27M MUTATION
    Kohanbash, Gary
    Okada, Kaori
    Liu, Shuming
    Lin, Yi
    Shrivastav, Shruti
    Nicolaides, Theodore
    Mueller, Sabine
    Pollack, Ian
    Carcaboso, Angel
    Hou, Yafei
    Okada, Hideho
    NEURO-ONCOLOGY, 2016, 18 : 67 - 67
  • [8] CRISPR BASED GENOME EDITING OF HUMAN T CELLS TO TARGET H3.3K27M MUTATION IN GLIOMAS
    Hegde, Bindu
    Roth, Theodore
    Nguyen, David
    Chheda, Zinal
    Apathy, Ryan
    Marson, Alex
    Okada, Hideho
    NEURO-ONCOLOGY, 2019, 21 : 127 - 127
  • [9] A MUTATION-SPECIFIC VACCINATION APPROACH FOR HISTON H3.3 K27M-MUTATED GLIOMAS
    Ochs, K.
    Ott, M.
    Bunse, L.
    Sahm, F.
    Bunse, T.
    von Deimling, A.
    Wick, W.
    Platten, M.
    NEURO-ONCOLOGY, 2016, 18 : 5 - 5
  • [10] TARGETING THE HISTONE H3.3-K27M MUTATION FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS
    Hashizume, Rintaro
    Ihara, Yuichiro
    Huang, Xi
    Lu Yu-Jen
    Tom, Maxwell
    Mueller, Sabine
    Gupta, Nalin
    Solomon, David
    Waldman, Todd
    Zhang, Zhiguo
    James, David
    NEURO-ONCOLOGY, 2013, 15 : 45 - 45
12345