The impact of oxidative stress damage induced by the environmental stressors on COVID-19

被引：45

作者：

Bakadia, Bianza Moise ^{[1
]}

Boni, Biaou Oscar Ode ^{[1
]}

Ahmed, Abeer Ahmed Qaed ^{[1
]}

Yang, Guang ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Dept Biomed Engn, Wuhan 430074, Peoples R China

来源：

LIFE SCIENCES | 2021年 / 264卷

基金：

中国国家自然科学基金;

关键词：

COVID-19; Environmental stressors; Chronic stress; Oxidative stress damage; Viral mutations; Vaccine; ACUTE RESPIRATORY SYNDROME; PSYCHOLOGICAL FLEXIBILITY; INFLEXIBILITY; MALNUTRITION; CORONAVIRUS; MUTATIONS; INCREASES; APOPTOSIS; SYMPTOMS; CHILDREN;

D O I：

10.1016/j.lfs.2020.118653

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a substantial stressor that is greatly impacting environmental sustainability. Besides, the different pre-existing environmental stressors and coronavirus disease-2019 (COVID-19)-related stressors are further worsening the effects of the viral disease by inducing the generation of oxidative stress. The generated oxidative stress results in nucleic acid damage associated with viral mutations, that could potentially reduce the effectiveness of COVID-19 management, including the vaccine approach. The current review is aimed to overview the impact of the oxidative stress damage induced by various environmental stressors on COVID-19. The available data regarding the COVID-19-related stressors and the effects of oxidative stress damage induced by the chronic stress, exposure to free radicals, and malnutrition are also analyzed to showcase the promising options, which could be investigated further for sustainable control of the pandemic.

引用

页数：10

共 113 条

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