Nordic clues for uncovering the aetiology of Multiple Sclerosis

被引:2
作者
Sipila, Jussi O. T. [1 ,2 ]
机构
[1] Siun Sote North Karelia Cent Hosp, Dept Neurol, Tikkamaentie 16, FI-80210 Joensuu, Finland
[2] Univ Turku, Clin Neurosci, Turku, Finland
关键词
Demyelinating disease; Epidemiology; Incidence; Multiple Sclerosis; Neuroimmunological disease;
D O I
10.1016/j.msard.2021.102804
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Our understanding of the etiology of multiple sclerosis (MS) is inadequate to effectively combat the increasing incidence and prevalence of the disease. Environmental factors are of crucial importance but more information about them is needed. Recent results of incidence trends over several decades in Denmark, Norway and Finland provide suggestions for further studies on the subject. Since incidence trends show marked differences by region and sex taking these factors into account when investigating birth cohort exposures could provide important new insights. Exposures during the first 15 years of life should be prioritized. International and multidisciplinary cooperation is needed.
引用
收藏
页数:2
相关论文
共 10 条
[1]   Multiple sclerosis in the far north - incidence and prevalence in Nordland County, Norway, 1970-2010 [J].
Benjaminsen, Espen ;
Olavsen, Johnny ;
Karlberg, Merethe ;
Alstadhaug, Karl B. .
BMC NEUROLOGY, 2014, 14
[2]   A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway [J].
Grytten, N. ;
Aarseth, J. H. ;
Lunde, H. M. B. ;
Myhr, K. M. .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2016, 87 (01) :100-105
[3]   Increased Female MS Incidence and Differences in Gender-Specific Risk in Medium- and High-Risk Regions in Finland from 1981-2010 [J].
Holmberg, Markus ;
Murtonen, Annukka ;
Elovaara, Irina ;
Sumelahti, Marja-Liisa .
MULTIPLE SCLEROSIS INTERNATIONAL, 2013, 2013
[4]  
Koch-Henriksen N, 2018, NEUROLOGY, V90, pE1954, DOI [10.1212/WNL.0000000000005612, 10.1212/wnl.0000000000005612]
[5]   Epidemiology in multiple sclerosis: a pilgrim's progress [J].
Kurtzke, John F. .
BRAIN, 2013, 136 :2904-2917
[6]   The EnvIMS Study: Design and Methodology of an International Case-Control Study of Environmental Risk Factors in Multiple Sclerosis [J].
Magalhaes, Sandra ;
Pugliatti, Maura ;
Casetta, Ilaria ;
Drulovic, Jelena ;
Granieri, Enrico ;
Holmoy, Trygve ;
Kampman, Margitta T. ;
Landtblom, Anne-Marie ;
Lauer, Klaus ;
Myhr, Kjell-Morten ;
Parpinel, Maria ;
Pekmezovic, Tatjana ;
Riise, Trond ;
Wolfson, David ;
Zhu, Bin ;
Wolfson, Christina .
NEUROEPIDEMIOLOGY, 2015, 44 (03) :173-181
[7]   Multiple sclerosis among first- and second-generation immigrants in Denmark: a population-based cohort study [J].
Nielsen, Nete Munk ;
Corn, Giulia ;
Frisch, Morten ;
Stenager, Egon ;
Koch-Henriksen, Nils ;
Wohlfahrt, Jan ;
Magyari, Melinda ;
Melbye, Mads .
BRAIN, 2019, 142 :1587-1597
[8]   Regional and temporal variation in the incidence of multiple sclerosis in Finland 1979-1993 [J].
Sumelahti, ML ;
Tienari, PJ ;
Wikström, J ;
Palo, J ;
Hakama, M .
NEUROEPIDEMIOLOGY, 2000, 19 (02) :67-75
[9]   Environmental and genetic risk factors for MS: an integrated review [J].
Waubant, Emmanuelle ;
Lucas, Robyn ;
Mowry, Ellen ;
Grayest, Jennifer ;
Olsson, Tomas ;
Alfredsson, Lars ;
Langer-Gould, Annette .
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2019, 6 (09) :1905-1922
[10]   High incidence and prevalence of MS in More and Romsdal County, Norway, 1950-2018 [J].
Willumsen, Johannes Sverre ;
Aarseth, Jan Harald ;
Myhr, Kjell-Morten ;
Midgard, Rune .
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2020, 7 (03)