Biological roles of the Lon ATP-dependent protease

被引：184

作者：

Tsilibaris, Virginie ^{[1
]}

Maenhaut-Michel, Genevieve ^{[1
]}

Van Melderen, Laurence ^{[1
]}

机构：

[1] Univ Libre Bruxelles, Lab Genet Procaryotes, IBMM, B-6041 Gosselies, Belgium

来源：

RESEARCH IN MICROBIOLOGY | 2006年 / 157卷 / 08期

关键词：

Lon; ATP-dependent proteolysis; protease; regulation; bacteria;

D O I：

10.1016/j.resmic.2006.05.004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Lon ATP-dependent protease plays a major role in protein quality control. An increasing number of regulatory proteins, however, are being identified as Lon substrates, thus indicating that in addition to its housekeeping function, Lon plays an important role in regulating many biological processes in bacteria. This review presents and discusses the involvement of Lon in different aspects of bacterial physiology, including cell differentiation, sporulation, pathogenicity and survival under starvation conditions. (c) 2006 Elsevier SAS. All rights reserved.

引用

页码：701 / 713

页数：13

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