Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): Challenges and guidelines

被引:0
|
作者
Woo, Xing Yi [1 ]
Srivastava, Anuj [1 ]
Graber, Joel H. [2 ]
Yadav, Vinod [1 ]
Sarsani, Vishal Kumar [3 ]
Simons, Al [3 ]
Beane, Glen [3 ]
Grubb, Stephen [3 ]
Ananda, Guruprasad [1 ]
Stafford, Grace [3 ]
Chuang, Jeffrey H. [1 ]
Airhart, Susan D. [3 ]
Karuturi, R. Krishna [1 ]
George, Joshy [1 ]
Bult, Carol J. [3 ]
机构
[1] Jackson Lab Genom Med, Farmington, CT USA
[2] MDI Biol Lab, Bar Harbor, ME USA
[3] Jackson Lab Mammalian Genet, Bar Harbor, ME USA
基金
美国国家卫生研究院;
关键词
D O I
10.1158/1538-7445.AM2019-1075
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1075
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
    Woo, Xing Yi
    Srivastava, Anuj
    Graber, Joel H.
    Yadav, Vinod
    Sarsani, Vishal Kumar
    Simons, Al
    Beane, Glen
    Grubb, Stephen
    Ananda, Guruprasad
    Liu, Rangjiao
    Stafford, Grace
    Chuang, Jeffrey H.
    Airhart, Susan D.
    Karuturi, R. Krishna Murthy
    George, Joshy
    Bult, Carol J.
    BMC MEDICAL GENOMICS, 2019, 12 (1)
  • [2] Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines
    Xing Yi Woo
    Anuj Srivastava
    Joel H. Graber
    Vinod Yadav
    Vishal Kumar Sarsani
    Al Simons
    Glen Beane
    Stephen Grubb
    Guruprasad Ananda
    Rangjiao Liu
    Grace Stafford
    Jeffrey H. Chuang
    Susan D. Airhart
    R. Krishna Murthy Karuturi
    Joshy George
    Carol J. Bult
    BMC Medical Genomics, 12
  • [3] Patient-derived xenografts (PDXs) as model systems for human cancer
    Invrea, Federica
    Rovito, Roberta
    Torchiaro, Erica
    Petti, Consalvo
    Isella, Claudio
    Medico, Enzo
    CURRENT OPINION IN BIOTECHNOLOGY, 2020, 63 : 151 - 156
  • [4] Functional study of glioblastoma (GBM) intratumour genomic heterogeneity and evolution using patient-derived xenografts (PDXs)
    Chigancas, V.
    Gonzalez-Junca, A.
    Parra, J. L.
    Mayor, R.
    Seoane, J.
    EUROPEAN JOURNAL OF CANCER, 2016, 61 : S1 - S1
  • [5] Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics
    Paul Guilhamon
    Lee M Butcher
    Nadege Presneau
    Gareth A Wilson
    Andrew Feber
    Dirk S Paul
    Moritz Schütte
    Johannes Haybaeck
    Ulrich Keilholz
    Jens Hoffman
    Mark T Ross
    Adrienne M Flanagan
    Stephan Beck
    Genome Medicine, 6
  • [6] Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics
    Guilhamon, Paul
    Butcher, Lee M.
    Presneau, Nadege
    Wilson, Gareth A.
    Feber, Andrew
    Paul, Dirk S.
    Scuette, Moritz
    Haybaeck, Johannes
    Keilholz, Ulrich
    Hoffman, Jens
    Ross, Mark T.
    Flanagan, Adrienne M.
    Beck, Stephan
    GENOME MEDICINE, 2014, 6
  • [7] Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice
    Yunsik Choi
    Sanghyuk Lee
    Kapyoul Kim
    Soo-Hyun Kim
    Yeun-Jun Chung
    Charles Lee
    Experimental & Molecular Medicine, 2018, 50 : 1 - 9
  • [8] A functional mutational profile of a compendium of 350 patient-derived tumor xenografts (PDXs).
    Krumbach, Rebekka
    Virajah, Jagatheswari
    Metcalfe, Thomas
    Fiebig, Heiner
    Vuaroqueaux, Vincent
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)
  • [9] Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice
    Choi, Yunsik
    Lee, Sanghyuk
    Kim, Kapyoul
    Kim, Soo-Hyun
    Chung, Yeun-Jun
    Lee, Charles
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, 50 : 1 - 9
  • [10] Establishment and Characterization of Patient-Derived Xenografts (PDXs) of Different Histology from Malignant Pleural Mesothelioma Patients
    Affatato, Roberta
    Mendogni, Paolo
    Del Gobbo, Alessandro
    Ferrero, Stefano
    Ricci, Francesca
    Broggini, Massimo
    Rosso, Lorenzo
    CANCERS, 2020, 12 (12) : 1 - 13