The role of internal water molecules in the structure and function of the rhodopsin family of G protein-coupled receptors

被引:105
作者
Pardo, Leonardo [1 ]
Deupi, Xavier
Dolker, Nicole
Lopez-Rodriguez, Maria Luz
Campillo, Mercedes
机构
[1] Univ Autonoma Barcelona, Lab Med Computac, Unitat Bioestadist, Fac Med, E-08193 Barcelona, Spain
[2] Univ Complutense Madrid, Dept Quim Organ 1, Fac Ciencias Quim, E-28040 Madrid, Spain
关键词
G protein-coupled receptors; molecular modeling; Pro-kink; structure-activity relationships; water;
D O I
10.1002/cbic.200600429
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:19 / 24
页数:6
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