Prevalence of 16S rRNA methylases in Gram-negative bacteria derived from companion animals and livestock in Japan

被引：3

作者：

Usui, Masaru ^{[1
]}

Kajino, Akari ^{[1
]}

Kon, Michiha ^{[1
]}

Fukuda, Akira ^{[1
]}

Sato, Tomomi ^{[1
]}

Shirakawa, Takahiro ^{[2
]}

Kawanishi, Michiko ^{[2
]}

Harada, Kazuki ^{[3
]}

Nakajima, Chie ^{[4
]}

Suzuki, Yasuhiko ^{[4
]}

Tamura, Yutaka ^{[1
]}

机构：

[1] Rakuno Gakuen Univ, Sch Vet Med, Lab Food Microbiol & Food Safety, Ebetsu, Hokkaido 0698501, Japan

[2] Minist Agr Forestry & Fisheries, Natl Vet Assay Lab, 1-15-1 Tokura, Kokubunji, Tokyo 1858511, Japan

[3] Tottori Univ, Dept Vet Internal Med, Minami 4-101, Tottori, Tottori 6808553, Japan

[4] Hokkaido Univ, Res Ctr Zoonosis Control, Div Bioresources, Sapporo, Hokkaido 0010020, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2019年 / 81卷 / 06期

关键词：

aminoglycoside resistance; companion animals; livestock; 16S rRNA methylases; FOOD-PRODUCING ANIMALS; ESCHERICHIA-COLI; ANTIMICROBIAL RESISTANCE; AMINOGLYCOSIDE RESISTANCE; PLASMID; GENES; FARMS; DOGS;

D O I：

10.1292/jvms.19-0144

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The emergence and spread of aminoglycoside-resistant bacteria are a public health concern. The acquisition of the genes encoding 16S rRNA methylases, such as armA, rmtA, and rmtB, confers high-level resistance to aminoglycosides. However, the prevalence has not been well investigated in Japanese veterinary fields. To determine the prevalence of 16S rRNA methylases in animals, we detected 16S rRNA methylases genes in Gram-negative bacteria from animals. Here, we report the isolation of rmtB and armA from two of the 446 Escherichia coli (0.5%) and one of the 103 Klebsiella spp. isolates (1.0%) from companion animals, respectively. However, none of the isolations were observed from 2445 E. coli isolates derived from livestock in Japan. The prevalence of 16S rRNA methylases in animals, especially in companion animals, should be carefully monitored in Japanese veterinary fields to avoid the spreading of the genes.

引用

页码：874 / 878

页数：5

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