A subset of viral transcripts packaged within human cytomegalovirus particles

被引：133

作者：

Bresnahan, WA ^{[1
]}

Shenk, T ^{[1
]}

机构：

[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

来源：

SCIENCE | 2000年 / 288卷 / 5475期

关键词：

D O I：

10.1126/science.288.5475.2373

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A human cytomegalovirus gene array was used to identify a previously unidentified class of viral transcripts, These transcripts, termed virion RNAs, were packaged within infectious virions and were delivered to the host cell on infection, This mechanism of herpesvirus gene expression allows for viral genes to be expressed within an infected cell immediately after virus entry and in the absence of transcription from the viral genome.

引用

页码：2373 / 2376

页数：4

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