Functional dissection of inhibitory microcircuits in the visual cortex

被引:8
作者
Kim, Kwansoo [1 ]
Kim, Jae-Hyun [1 ]
Song, You-Hyang [1 ]
Lee, Seung-Hee [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Dept Biol Sci, 291 Daehak Ro, Daejeon 34141, South Korea
基金
新加坡国家研究基金会;
关键词
Visual cortex; Cortical microcircuit; GABAergic neurons; Inhibitory neurons; Visual processing; Orientation selectivity; ORIENTATION SELECTIVITY; GABAERGIC NEURONS; RECEPTIVE-FIELDS; CORTICAL-NEURONS; EXPRESSING INTERNEURONS; BASAL FOREBRAIN; IN-VIVO; CELL-TYPE; MECHANISMS; DYNAMICS;
D O I
10.1016/j.neures.2016.09.003
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Cerebral cortex contains various types of GABAergic neurons exerting local inhibition. Although the number of GABAergic inhibitory neurons is much smaller than glutamatergic excitatory neurons, they show greater diversity in their morphological And physiological properties. Genetic markers for distinct subclasses of GABAergic neurons have been identified, and technical advances achieved in the past few decades have brought about a demonstration of a unique function of each sub-class of GABAergic neurons in the cortex. In particular, visual processing in the cortex requires inhibitory function of various GABAergic neurons. Here, we summarize current understandings on the function of inhibitory neurons in the cortex, especially focusing on their roles in visual processing. (C) 2016 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.
引用
收藏
页码:70 / 76
页数:7
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