Ring closing metathesis reactions of isoquinoline and β-carboline enamines

被引：27
作者：
Evans, P [1 ]
Grigg, R [1 ]
York, M [1 ]
机构：
[1] Univ Leeds, Sch Chem, MIDAS Ctr, Leeds LS2 9JT, W Yorkshire, England
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 20期
基金：
英国工程与自然科学研究理事会;
关键词：
metathesis; ruthenium catalyst; enamines; isoquinolines; beta-carbolines; basicity;
D O I：
10.1016/S0040-4039(00)00489-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ring closing metathesis of enamines derived from isoquinolines and beta-carboline occurs in DCM at room temperature in good yields. The products of ring closing metathesis bear close structural relationships to many alkaloidal natural products and are obtained in yields that bear approximate inverse proportionality to the calculated basicity of the enamine starting material. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：3967 / 3970
页数：4
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