Sarcotoxin Effect on Leukocytic Finding and Phagocytic Activity in Mice

The total leukocytes counts in three groups of inoculation (3, 5 and 7 mg) with Sarcotoxin of Sarcocystis gigantea showed severe depression in their numbers comparing with control group (2200, 2375, 1950 and 5500) respectively, but there was no changes in effect between two post inoculation period. Appearance of lowering in numbers of lymphocytes, neutrophils, monocytes, eosinophils in inoculation groups comparing with control one was significantly. Blood stream clearance of Nitroblue Tetrazolium, stain (NBT) has been evaluated to establish the phagocytic activity of neutrophils from mice experimentally inoculated with Sarcotoxin, the phagocytic cells calculated and there was decreasing in numbers of these cells in the treatment groups (inoculation) comparing with control one significantly (316, 284, 225 and 778), respectively. Hours of post inoculation time had no influences on these parameters (total, differential leukocytes count and phagocytic activity).