Toward neuroprotective treatments of Parkinson's disease

被引：24
作者：
Kim, Kwang-Soo [1 ,2 ]
机构：
[1] Harvard Med Sch, Program Neurosci, Mol Neurobiol Lab, Boston, MA 02115 USA
[2] Harvard Med Sch, McLean Hosp, Dept Psychiat, 115 Mill St, Belmont, MA 02478 USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2017年 / 114卷 / 15期
关键词：
DOPAMINE NEURONS; NUCLEAR RECEPTORS; NURR1; PATHWAY; MODELS;
D O I：
10.1073/pnas.1703362114
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：3795 / 3797
页数：3
相关论文
共 20 条
[1]   How to make a midbrain dopaminergic neuron [J].
Arenas, Ernest ;
Denham, Mark ;
Villaescusa, J. Carlos .
DEVELOPMENT, 2015, 142 (11) :1918-1936
[2]   Wnt1-Imx1a Forms a Novel Autoregulatory Loop and Controls Midbrain Dopaminergic Differentiation Synergistically with the SHH-FoxA2 Pathway [J].
Chung, Sangmi ;
Leung, Amanda ;
Han, Baek-Soo ;
Chang, Mi-Yoon ;
Moon, Jung-Il ;
Kim, Chun-Hyung ;
Hong, Sunghoi ;
Pruszak, Jan ;
Isacson, Ole ;
Kim, Kwang-Soo .
CELL STEM CELL, 2009, 5 (06) :646-658
[3]   Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates [J].
Collier, Timothy J. ;
Kanaan, Nicholas M. ;
Kordower, Jeffrey H. .
NATURE REVIEWS NEUROSCIENCE, 2011, 12 (06) :359-366
[4]   MODIFICATION OF PARKINSONISM - CHRONIC TREATMENT WITH L-DOPA [J].
COTZIAS, GC ;
PAPAVASI.PS ;
GELLENE, R .
NEW ENGLAND JOURNAL OF MEDICINE, 1969, 280 (07) :337-&
[5]   Parkinson's disease: Mechanisms and models [J].
Dauer, W ;
Przedborski, S .
NEURON, 2003, 39 (06) :889-909
[6]   NURR1 in Parkinson disease-from pathogenesis to therapeutic potential [J].
Decressac, Mickael ;
Volakakis, Nikolaos ;
Bjorklund, Anders ;
Perlmann, Thomas .
NATURE REVIEWS NEUROLOGY, 2013, 9 (11) :629-636
[7]   Nurr1-Based Therapies for Parkinson's Disease [J].
Dong, Jie ;
Li, Song ;
Mo, Jing-Lin ;
Cai, Huai-Bin ;
Le, Wei-Dong .
CNS NEUROSCIENCE & THERAPEUTICS, 2016, 22 (05) :351-359
[8]   Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons [J].
Kadkhodaei, Banafsheh ;
Ito, Takehito ;
Joodmardi, Eliza ;
Mattsson, Bengt ;
Rouillard, Claude ;
Carta, Manolo ;
Muramatsu, Shin-Ichi ;
Sumi-Ichinose, Chiho ;
Nomura, Takahide ;
Metzger, Daniel ;
Chambon, Pierre ;
Lindqvist, Eva ;
Larsson, Nils-Goeran ;
Olson, Lars ;
Bjorklund, Anders ;
Ichinose, Hiroshi ;
Perlmann, Thomas .
JOURNAL OF NEUROSCIENCE, 2009, 29 (50) :15923-15932
[9]   4-amino-7-chloroquinoline derivatives for treating Parkinson's disease: implications for drug discovery [J].
Kim, Chun-Hyung ;
Leblanc, Pierre ;
Kim, Kwang-Soo .
EXPERT OPINION ON DRUG DISCOVERY, 2016, 11 (04) :337-341
[10]   Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease [J].
Kim, Chun-Hyung ;
Han, Baek-Soo ;
Moon, Jisook ;
Kim, Deog-Joong ;
Shin, Joon ;
Rajan, Sreekanth ;
Quoc Toan Nguyen ;
Sohn, Mijin ;
Kim, Won-Gon ;
Han, Minjoon ;
Jeong, Inhye ;
Kim, Kyoung-Shim ;
Lee, Eun-Hye ;
Tu, Yupeng ;
Naffin-Olivos, Jacqueline L. ;
Park, Chang-Hwan ;
Ringe, Dagmar ;
Yoon, Ho Sup ;
Petsko, Gregory A. ;
Kim, Kwang-Soo .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (28) :8756-8761
12