Genes basis of temperament and personality

被引:0
作者
Alfimova, MV [1 ]
Trubnikov, BI [1 ]
机构
[1] Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow 109801, Russia
关键词
D O I
暂无
中图分类号
G44 [教育心理学];
学科分类号
0402 ; 040202 ;
摘要
According to genetics of behavior data contribution of genetic factors in difference of human temperament characteristics is 30-60 %, more over,temperament features depend on summary influence or interaction of many genes with little effects. From the middle of 90-s concrete genes responsible for individual differences in temperament features are searched. It became possible due to exploration of genes which encode albumens with already known functions in brain biochemical processes,as well as to creation of methods that allow to define relatively easy which gene's allele forms contain genotype of this or that person. As of now reliable and reproduced results in investigation of genes basis of temperament: are not yet obtained. One of the most perspective lines of investigation is search of associations between 1) genes involved in functioning of dofamin system,and those dynamic peculiarities of behavior which are connected with activity and sociability/estrangability, 2) serotonin transporting gene and anxiety,3) tryptophan hydrocsilazagene and aggression.
引用
收藏
页码:128 / +
页数:13
相关论文
共 97 条
  • [1] [Anonymous], BIOL PSYCHIAT
  • [2] The serotonin transporter gene and peer-rated neuroticism
    Ball, D
    Hill, L
    Freeman, B
    Eley, TC
    Strelau, J
    Riemann, R
    Spinath, FM
    Angleitner, A
    Plomin, R
    [J]. NEUROREPORT, 1997, 8 (05) : 1301 - 1304
  • [3] Psychobiology of novelty seeking and drug seeking behavior
    Bardo, MT
    Donohew, RL
    Harrington, NG
    [J]. BEHAVIOURAL BRAIN RESEARCH, 1996, 77 (1-2) : 23 - 43
  • [4] Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking
    Benjamin, J
    Li, L
    Patterson, C
    Greenberg, BD
    Murphy, DL
    Hamer, DH
    [J]. NATURE GENETICS, 1996, 12 (01) : 81 - 84
  • [5] Benjamin J, 1998, HUM PSYCHOPHARM CLIN, V13, P11, DOI 10.1002/(SICI)1099-1077(199801)13:1<11::AID-HUP933>3.0.CO
  • [6] 2-9
  • [7] Association of polymorphisms of dopamine D-2 receptor (DRD2), and dopamine transporter (DAT(1)) genes with schizoid/avoidant behaviors (SAB)
    Blum, K
    Braverman, ER
    Wu, S
    Cull, JG
    Chen, TJH
    Gill, J
    Wood, R
    Eisenberg, A
    Sherman, M
    Davis, KR
    Matthews, D
    Fischer, L
    Schnautz, N
    Walsh, W
    Pontius, AA
    Zedar, M
    Kaats, G
    Comings, DE
    [J]. MOLECULAR PSYCHIATRY, 1997, 2 (03) : 239 - 246
  • [8] Dopamine D2 receptor density and personal detachment in healthy subjects
    Breier, A
    Kestler, L
    Adler, C
    Elman, I
    Wiesenfeld, N
    Malhotra, A
    Pickar, D
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 1998, 155 (10) : 1440 - 1442
  • [9] PERSONALITY AND PSYCHOPATHOLOGY - GENETIC PERSPECTIVES
    CAREY, G
    DILALLA, DL
    [J]. JOURNAL OF ABNORMAL PSYCHOLOGY, 1994, 103 (01) : 32 - 43
  • [10] The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus
    Chang, FM
    Kidd, JR
    Livak, KJ
    Pakstis, AJ
    Kidd, KK
    [J]. HUMAN GENETICS, 1996, 98 (01) : 91 - 101