Obesity and Prevalence of Cardiovascular Diseases and Prognosis-The Obesity Paradox Updated

被引：347

作者：

Lavie, Carl J. ^{[1
]}

De Schutter, Alban ^{[1
]}

Parto, Parham ^{[1
]}

Jahangir, Eiman ^{[1
]}

Kokkinos, Peter ^{[2
]}

Ortega, Francisco B. ^{[3
]}

Arena, Ross ^{[4
]}

Milani, Richard V. ^{[1
]}

机构：

[1] Univ Queensland, John Ochsner Heart & Vasc Inst, Sch Med, Dept Cardiovasc Dis,Ochsner Clin Sch, New Orleans, LA 70121 USA

[2] Georgetown Univ, Sch Med, Dept Cardiol, Vet Affairs Med Ctr, Washington, DC USA

[3] Univ Granada, Dept Phys Educ & Sports, PROFITH PROmoting FITness & Hlth Phys Act Res Grp, Fac Sports Sci, Granada, Spain

[4] Univ Illinois, Coll Appl Sci, Dept Kinesiol & Nutr, Dept Phys Therapy,Integrat Physiol Lab, Chicago, IL USA

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2016年 / 58卷 / 05期

关键词：

Obesity; Cardiovascular diseases; Cardiorespiratory fitness; Weight loss; CORONARY-HEART-DISEASE; BODY-MASS INDEX; ALL-CAUSE MORTALITY; PRESERVED EJECTION FRACTION; LEFT-VENTRICULAR GEOMETRY; ATRIAL VOLUME INDEX; CARDIORESPIRATORY FITNESS; WEIGHT-LOSS; ARTERY-DISEASE; PHYSICAL-ACTIVITY;

D O I：

10.1016/j.pcad.2016.01.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence and severity of obesity have increased in the United States and most of the Westernized World over recent decades, reaching worldwide epidemics. Since obesity worsens most of the cardiovascular disease (CVD) risk factors, not surprisingly, most CVDs, including hypertension, coronary heart disease, heart failure, and atrial fibrillation, are all increased in the setting of obesity. However, many studies and meta-analyses have demonstrated an obesity paradox with regards to prognosis in CVD patients, with often the overweight and mildly obese having a better prognosis than do their leaner counterparts with the same CVD. The implication for fitness to markedly alter the relationship between adiposity and prognosis and the potential impact of weight loss, in light of the obesity paradox, are all reviewed. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：537 / 547

页数：11

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