Proteinases in cardiovascular aneurysms and rupture: targets for therapy?

被引：34

作者：

Carmeliet, P ^{[1
]}

机构：

[1] Catholic Univ Louvain VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2000年 / 105卷 / 11期

关键词：

D O I：

10.1172/JCI10242

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：1519 / 1520

页数：2

共 15 条

[1] Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model [J].

Allaire, E ;

Forough, R ;

Clowes, W ;

Starcher, B ;

Clowes, AW .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (07) :1413-1420

[2] Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1 [J].

Allaire, E ;

Hasenstab, D ;

Kenagy, RD ;

Starcher, B ;

Clowes, MM ;

Clowes, AW .

CIRCULATION, 1998, 98 (03) :249-255

[3] Cell and extracellular matrix rejection in arterial concordant and discordant xenografts in the rat [J].

Allaire, E ;

Mandet, C ;

Bruneval, P ;

Bensenane, S ;

Becquemin, JP ;

Michel, JB .

TRANSPLANTATION, 1996, 62 (06) :794-803

[4] Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation [J].

Carmeliet, P ;

Moons, L ;

Lijnen, HR ;

Baes, M ;

Lemaitre, V ;

Tipping, P ;

Drew, A ;

Eeckhout, Y ;

Shapiro, S ;

Lupu, F ;

Collen, D .

NATURE GENETICS, 1997, 17 (04) :439-444

[5] Experimental techniques and models in the study of the development and treatment of abdominal aortic aneurysm [J].

Carrell, TWG ;

Smith, A ;

Burnand, KG .

BRITISH JOURNAL OF SURGERY, 1999, 86 (03) :305-312

[6] Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms [J].

Curci, JA ;

Liao, SX ;

Huffman, MD ;

Shapiro, SD ;

Thompson, RW .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (11) :1900-1910

[7]

Dalrymple-Hay M J, 1998, Semin Thorac Cardiovasc Surg, V10, P111

[8] Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure [J].

Heymans, S ;

Luttun, A ;

Nuyens, D ;

Theilmeier, G ;

Creemers, E ;

Moons, L ;

Dyspersin, GD ;

Cleutjens, JPM ;

Shipley, M ;

Angellilo, A ;

Levi, M ;

Nübe, O ;

Baker, A ;

Keshet, E ;

Lupu, F ;

Herbert, JM ;

Smits, JFM ;

Shapiro, SD ;

Baes, M ;

Borgers, M ;

Collen, D ;

Daemen, MJAP ;

Carmeliet, P .

NATURE MEDICINE, 1999, 5 (10) :1135-1142

[9] DEMONSTRATION OF INTERSTITIAL COLLAGENASE IN ABDOMINAL AORTIC-ANEURYSM DISEASE [J].

IRIZARRY, E ;

NEWMAN, KM ;

GANDHI, RH ;

NACKMAN, GB ;

HALPERN, V ;

WISHNER, S ;

SCHOLES, JV ;

TILSON, MD .

JOURNAL OF SURGICAL RESEARCH, 1993, 54 (06) :571-574

[10] PLASMINOGEN-ACTIVATOR EXPRESSION IN HUMAN ATHEROSCLEROTIC LESIONS [J].

LUPU, F ;

HEIM, DA ;

BACHMANN, F ;

HURNI, M ;

KAKKAR, VV ;

KRUITHOF, EKO .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (09) :1444-1455

← 1 2 →