MANAGEMENT OF ENDOCRINE DISEASE Metabolic effects of bariatric surgery

被引:27
作者
Corcelles, Ricard [1 ,2 ]
Daigle, Christopher R. [1 ]
Schauer, Philip R. [1 ]
机构
[1] Cleveland Clin, Bariatr & Metab Inst, Cleveland, OH 44195 USA
[2] Hosp Clin Barcelona, Fundacio Clin Recerca Biomed, Inst Digest & Metab Dis, Dept Gastrointestinal Surg, Barcelona, Spain
关键词
Y GASTRIC BYPASS; TYPE-2; DIABETES-MELLITUS; GLUCAGON-LIKE PEPTIDE-1; LONG-TERM MORTALITY; WEIGHT-LOSS; OBESE-PATIENTS; SLEEVE GASTRECTOMY; GLUCOSE-TOLERANCE; GUT MICROBIOTA; POTENTIAL CONTRIBUTION;
D O I
10.1530/EJE-15-0533
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity is associated with an increased risk of type 2 diabetes, hypertension, dyslipidemia, cardiovascular disease, osteoarthritis, numerous cancers and increased mortality. It is estimated that at least 2.8 million adults die each year due to obesity-related cardiovascular disease. Increasing in parallel with the global obesity problem is metabolic syndrome, which has also reached epidemic levels. Numerous studies have demonstrated that bariatric surgery is associated with significant and durable weight loss with associated improvement of obesity-related comorbidities. This review aims to summarize the effects of bariatric surgery on the components of metabolic syndrome (hyperglycemia, hyperlipidemia and hypertension), weight loss, perioperative morbidity and mortality, and the long-term impact on cardiovascular risk and mortality.
引用
收藏
页码:R19 / R28
页数:10
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