Synthesis of "bioinspired'' copolymers: experimental and theoretical investigation on poly(vinyl benzyl thymine-co-triethyl ammonium chloride)

Bioinspired'' copolymers based on vinylbenzyl thymine (VBT) and an ionically-charged monomer, such as vinylbenzyl triethylammonium chloride (VBA), were synthesized and theoretically investigated. These water-soluble copolymers are polystyrene- (PS) based, and their structure mimics DNA. In the presence of short-wavelength UV light, the thymine groups dimerize into non-toxic, environmentally benign, and biodegradable photo-resistant materials. Copolymerizations with different comonomer ratios were carried out at 65 degrees C. Samples were taken along the reactions to determine monomer conversion, chemical composition, and molecular weight distribution. While average molecular weights fall along the reaction, the average composition remains almost constant and coincident with the initial comonomer ratios, thus indicating a similar reactivity of all the comonomer radicals. A mathematical model was developed that simulates the synthesis of the base biopolymer, in the sense of predicting the evolution of the global reaction variables and molecular structure of the polymer. The termination and propagation kinetic constants were adjusted to the experimental data. The resulting values are quite different to those of a normal styrene homopolymerization, thus suggesting a noticeable effect of the solvent and the comonomer pending groups. [Casis, N.; Luciani, C. V.; Vich Berlanga, J.; Estenoz, D. A.; Martino, D. M.; Meira, G. R.] UNL, CONICET, INTEC, RA-3000 Santa Fe, Argentina; [Martino, D. M.] UNL, FBCB, RA-3000 Santa Fe, Argentina Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); National University of the Littoral; National University of the Littoral Estenoz, DA (corresponding author), UNL, CONICET, INTEC, Guemes 3450, RA-3000 Santa Fe, Argentina. destenoz@ceride.gov.ar; dmartino@intec.unl.edu.ar Universidad Nacional del Litoral; ANPCyT; CONICET (Argentina); National Science Foundation [0556272]; Pfizer Pharmaceuticals (USA); Office Of Internatl Science &Engineering; Office Of The Director [0556272] Funding Source: National Science Foundation Universidad Nacional del Litoral; ANPCyT(ANPCyT); CONICET (Argentina)(Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET)); National Science Foundation(National Science Foundation (NSF)); Pfizer Pharmaceuticals (USA)(Pfizer); Office Of Internatl Science &Engineering; Office Of The Director(National Science Foundation (NSF)NSF - Office of the Director (OD)) The authors thank the Center for Green Chemistry, University of Massachusetts, Lowell for providing the VBT and VBA monomers. Financial support was received from Universidad Nacional del Litoral, ANPCyT, CONICET (Argentina); the National Science Foundation under Grant No. 0556272 and Pfizer Pharmaceuticals (USA). 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Lett. Rev. 2007 1 1 65 72 10.1080/17518250701757007 http://dx.doi.org/10.1080/17518250701757007 8 Chemistry, Multidisciplinary; Green & Sustainable Science & Technology Science Citation Index Expanded (SCI-EXPANDED) Chemistry; Science & Technology - Other Topics V18HJ Green Published 2024-02-26 WOS:000207995600012 J Cassell, BG; Olsonl, KM; McAllister, AJ Cassell, B. G.; Olsonl, K. M.; McAllister, A. J. Comparison of yield in Holsteins, Jerseys, and reciprocal crosses in the Virginia Polytechnic Institute and State University - Kentucky crossbreeding trial JOURNAL OF ANIMAL SCIENCE English Meeting Abstract crossbreeding; heterosis; production [Cassell, B. G.; Olsonl, K. M.] Virginia Polytech Inst & State Univ, Blacksburg, VA 24061 USA; [McAllister, A. J.] Univ Kentucky, Lexington, KY USA Virginia Polytechnic Institute & State University; University of Kentucky 0 0 0 0 0 AMER SOC ANIMAL SCIENCE SAVOY 1111 NORTH DUNLAP AVE, SAVOY, IL 61874 USA 0021-8812 J ANIM SCI J. Anim. Sci. 2007 85 1 597 597 1 Agriculture, Dairy & Animal Science Science Citation Index Expanded (SCI-EXPANDED) Agriculture 213UN 2024-02-26 WOS:000249692701842 J Cassell, BG; Olson, KM; McAllister, AJ Cassell, B. G.; Olson, K. M.; McAllister, A. J. Comparison of yield in Holsteins, Jerseys, and reciprocal crosses in the Virginia Polytechnic Institute and State University - Kentucky crossbreeding trial POULTRY SCIENCE English Meeting Abstract crossbreeding; heterosis; production [Cassell, B. G.; Olson, K. M.] Virginia Polytech Inst & State Univ, Blacksburg, VA 24061 USA; [McAllister, A. J.] Univ Kentucky, Lexington, KY USA Virginia Polytechnic Institute & State University; University of Kentucky 0 0 0 0 0 POULTRY SCIENCE ASSOC INC SAVOY 1111 N DUNLAP AVE, SAVOY, IL 61874-9604 USA 0032-5791 POULTRY SCI Poult. Sci. 2007 86 1 597 597 1 Agriculture, Dairy & Animal Science Science Citation Index Expanded (SCI-EXPANDED) Agriculture 213UM 2024-02-26 WOS:000249692601842 J Cassell, SE; Bieber, JD; Rich, P; Tutuncu, ZN; Lee, SJ; Kalunian, KC; Wu, CW; Kavanaugh, A Cassell, Sarah E.; Bieber, Jeffry D.; Rich, Phoebe; Tutuncu, Zuhre N.; Lee, Susan J.; Kalunian, Kenneth C.; Wu, Christopher W.; Kavanaugh, Arthur The modified nail psoriasis severity index: Validation of an instrument to assess psoriatic nail involvement in patients with psoriatic arthritis JOURNAL OF RHEUMATOLOGY English Article Nail Psoriasis Severity Index; psoriatic arthritis; psoriasis; nail; outcome measures DISTAL INTERPHALANGEAL JOINT; DISEASE; RESOLUTION; THERAPY; SKIN Objective. Patients with psoriasis and psoriatic arthritis (PsA) commonly have nail involvement. There is no validated psoriatic nail assessment tool. Recently, investigators developed the Nail Psoriasis Severity Index (NAPSI). Beginning with NAPSI, our goal was to validate a psoriatic nail assessment tool for use in clinical trials, and investigate correlations between nail and other PsA features. Methods. Fingernails of 29 patients with PsA were photographed and scored. Clinical data were collected. Using the original NAPSI, analysis revealed high interrater variability of nail scores. Twenty patients' photographs were regraded using the modified NAPSI (mNAPSI). Results. The mNAPSI scores had excellent interrater reliability (Cronbach's alpha 0.98). Nail scores and physicians' global nail severity visual analog scores showed good inter- and intrarater correlations (Spearman's rho 0.85 and 0.90-0.99, respectively; p < 0.01). Several clinical measures correlated with nail scores. Conclusion. The mNAPSI demonstrated excellent interrater reliability and construct validity, and may be a valuable tool. Univ Calif San Diego, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA; Oregon Hlth Sci Univ, Portland, OR 97201 USA University of California System; University of California San Diego; Oregon Health & Science University Kavanaugh, A (corresponding author), Univ Calif San Diego, Div Rheumatol Allergy & Immunol, 9500 Gilman Dr,Mail Code 0943, La Jolla, CA 92093 USA. akavanaugh@ucsd.edu Kalunian, Kenneth/L-4471-2019; Kalunian, Kenneth/AAK-6424-2020 Kalunian, Kenneth/0000-0003-0261-3102 Bianchi L, 2005, J AM ACAD DERMATOL, V52, P736, DOI 10.1016/j.jaad.2004.09.012; Cassell S, 2006, J RHEUMATOL, V33, P1452; Cassetty CT, 2005, J AM ACAD DERMATOL, V52, P1101, DOI 10.1016/j.jaad.2005.01.101; deJong EMGJ, 1996, DERMATOLOGY, V193, P300, DOI 10.1159/000246274; Elkayam O, 2000, CLIN RHEUMATOL, V19, P301, DOI 10.1007/PL00011173; Gladman DD, 1998, RHEUM DIS CLIN N AM, V24, P829, DOI 10.1016/S0889-857X(05)70044-2; GLADMAN DD, 1995, J RHEUMATOL, V22, P675; JONES SM, 1994, BRIT J RHEUMATOL, V33, P834; OMURA EF, 1985, DERMATOL CLIN, V3, P531, DOI 10.1016/S0733-8635(18)30891-X; Parrish CA, 2005, J AM ACAD DERMATOL, V53, P745, DOI 10.1016/j.jaad.2004.11.044; Reich K, 2005, LANCET, V366, P1367, DOI 10.1016/S0140-6736(05)67566-6; Rich P, 2005, J AM ACAD DERMATOL, V53, P746, DOI 10.1016/j.jaad.2005.03.008; Rich P, 2003, J AM ACAD DERMATOL, V49, P206, DOI 10.1067/S0190-9622(03)00910-1; RICHTER MR, 1999, J RHEUMATOL, V26, P1752; Salomon O, 2003, J CUTAN MED SURG, V7, P317, DOI 10.1007/s10227-002-0143-0; Scarpa R, 2004, CLIN RHEUMATOL, V23, P27, DOI 10.1007/s10067-003-0817-z; Schon MP, 2005, NEW ENGL J MED, V352, P1899, DOI 10.1056/NEJMra041320; Tan AL, 2006, ARTHRITIS RHEUM-US, V54, P1328, DOI 10.1002/art.21736; Williamson L, 2004, RHEUMATOLOGY, V43, P790, DOI 10.1093/rheumatology/keh198 19 129 144 2 4 J RHEUMATOL PUBL CO TORONTO 920 YONGE ST, SUITE 115, TORONTO, ONTARIO M4W 3C7, CANADA 0315-162X J RHEUMATOL J. Rheumatol. JAN 2007 34 1 123 129 7 Rheumatology Science Citation Index Expanded (SCI-EXPANDED) Rheumatology 125UC 17216680 2024-02-26 WOS:000243467300022 J Cassia de Aquiho, RD; Tucunduva Philippi, S Cassia de Aquiho, Rita De; Tucunduva Philippi, Sonia Application of the nutritional risk screening (NRS 2002): An analysis in three hundred hospitalized patients in Sao Paulo, Brazil ANNALS OF NUTRITION AND METABOLISM English Meeting Abstract Univ Sao Paulo, Dept Nutr, Sch Publ Hlth, Sao Paulo, Brazil Universidade de Sao Paulo 0 0 0 0 0 KARGER BASEL ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND 0250-6807 ANN NUTR METAB Ann. Nutr. Metab. 2007 51 1 193 194 2 Endocrinology & Metabolism; Nutrition & Dietetics Science Citation Index Expanded (SCI-EXPANDED) Endocrinology & Metabolism; Nutrition & Dietetics 192FE 2024-02-26 WOS:000248185400472 J Cassier, P; Fayette, J; Ray-Coquard, I; Bui, B; Duffaud, F; Adonis, A; Viens, P; Rios, M; Cupissol, D; Perol, D; Blay, J; Le Cesne, A Cassier, P.; Fayette, J.; Ray-Coquard, I.; Bui, B.; Duffaud, F.; Adonis, A.; Viens, P.; Rios, M.; Cupissol, D.; Perol, D.; Blay, J.; Le Cesne, A. Outcome of patients with locally advanced gist receiving imatinib mesylate in a prospective trial ANNALS OF ONCOLOGY English Meeting Abstract 9th World Congress on Gastrointestinal Cancer JUN 28-JUL 01, 2007 Barcelona, SPAIN Hop Edouard Herriot, Lyon, France; Ctr Leon Berard, F-69373 Lyon, France; Inst Bergonie, Bordeaux, France; Hop Enfants La Timone, Marseille, France; Ctr Oscar Lambret, F-59020 Lille, France; Inst J Paoli I Calmettes, F-13009 Marseille, France; Ctr Val Aurelle, Montpellier, France; Inst Gustave Roussy, Villejuif, France CHU Lyon; UNICANCER; Centre Leon Berard; UNICANCER; Institut Bergonie; Aix-Marseille Universite; Assistance Publique-Hopitaux de Marseille; UNICANCER; Centre Oscar Lambret; UNICANCER; Institut Paoli-Calmette (IPC); UNICANCER; Universite de Montpellier; Institut Regional du Cancer Montpellier / Val d'Aurelle (ICM); UNICANCER; Gustave Roussy Blay, Jean-Yves/N-3966-2016; d, p/GWC-4283-2022 Blay, Jean-Yves/0000-0001-7190-120X; 0 0 0 0 0 OXFORD UNIV PRESS OXFORD GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND 0923-7534 ANN ONCOL Ann. Oncol. 2007 18 7 VII105 VII106 2 Oncology Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED) Oncology 207WC 2024-02-26 WOS:000249280800352 J Castagna, M; Brilli, L; Pilli, T; Montanaro, A; Guarino, E; Capezzone, M; Cipri, C; Fioravanti, C; Sestini, F; Ghezzi, M; Ciuoli, C; Pacini, F Castagna, M.; Brilli, L.; Pilli, T.; Montanaro, A.; Guarino, E.; Capezzone, M.; Cipri, C.; Fioravanti, C.; Sestini, F.; Ghezzi, M.; Ciuoli, C.; Pacini, F. Is a 2nd RH-TSH stimulation test (2-3 years after the first assessment) needed in patients with differentiated thyroid carcinoma (DTC) who have undetectable basal serum thyroglobulin (Tg) levels? HORMONE RESEARCH English Meeting Abstract [Castagna, M.; Brilli, L.; Pilli, T.; Montanaro, A.; Guarino, E.; Capezzone, M.; Cipri, C.; Fioravanti, C.; Sestini, F.; Ghezzi, M.; Ciuoli, C.; Pacini, F.] Univ Siena, I-53100 Siena, Italy University of Siena Capezzone, Marco/AAL-2308-2020; Capezzone, Marco/AAA-3137-2022; Capezzone, Marco/AAD-1776-2022; Capezzone, Marco/AAA-3080-2022 Capezzone, Marco/0000-0001-8624-5831; Capezzone, Marco/0000-0001-8624-5831 0 0 0 0 0 KARGER BASEL ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND 0301-0163 HORM RES Horm. Res. 2007 68 3 28 28 1 Endocrinology & Metabolism Science Citation Index Expanded (SCI-EXPANDED) Endocrinology & Metabolism 240WB 2024-02-26 WOS:000251617800072 J Castagnet, PI; Nussbaum, RL; Murphy, EJ Castagnet, P. I.; Nussbaum, R. L.; Murphy, E. J. α-synuclein gene ablation decreases astrocyte fatty acid uptake and alters fatty acid trafficking JOURNAL OF MOLECULAR NEUROSCIENCE English Meeting Abstract International Workshop on Brain Uptake and Utilization of Fatty Acids, Lipids and Lipoproteins OCT 07-09, 2004 Bethesda, MD NHGRI, NIH, Genet Dis Res Branch, Bethesda, MD 20892 USA National Institutes of Health (NIH) - USA; NIH National Human Genome Research Institute (NHGRI) 0 0 0 0 0 HUMANA PRESS INC TOTOWA 999 RIVERVIEW DRIVE SUITE 208, TOTOWA, NJ 07512 USA 0895-8696 J MOL NEUROSCI J. Mol. Neurosci. 2007 33 1 134 134 1 Biochemistry & Molecular Biology; Neurosciences Conference Proceedings Citation Index - Science (CPCI-S); Science Citation Index Expanded (SCI-EXPANDED) Biochemistry & Molecular Biology; Neurosciences & Neurology 213MD 2024-02-26 WOS:000249670800032 J Castanet, G; Lemoine, F Castanet, G.; Lemoine, F. Heat transfer within combusting droplets PROCEEDINGS OF THE COMBUSTION INSTITUTE English Article droplets; evaporation; combustion; temperature measurements; heat and mass transfers TEMPERATURE-MEASUREMENTS; STREAM; EVAPORATION The improvement of the basic understanding of heat transfer in sprays is a key point in many engineering applications. In this paper, the temperature field within combusting ethanol droplets in linear stream is investigated by the two-color laser induced fluorescence technique. Additionally, a heat transfer model within the droplet is developed, taking into account both heat conduction and heat advection by the droplet internal fluid circulation, according to the Hill vortex pattern. Heat and mass exchanges between the liquid and the gas phases are described within the framework of the quasi-steady approach and the film theory. Comparisons between measurements and computational results allow determining the intensity of the Hill vortex related to the maximum velocity at the droplet surface. An expression of the friction coefficient for combusting and interacting droplets is derived from the case of an isolated droplet and a good agreement with the experimental data is observed. (C) 2006 The Combustion Institute. Published by Elsevier Inc. All rights reserved. [Lemoine, F.] CNRS, LEMTA, UMR, F-54504 Vandaeuvre Nancy, France; [Castanet, G.] Tech Univ Darmstadt, Fachgebiet Stromungslehre & Aerodynam, D-64287 Darmstadt, Germany Centre National de la Recherche Scientifique (CNRS); Technical University of Darmstadt Lemoine, F (corresponding author), CNRS, LEMTA, UMR, 2 Ave Foret Haye, F-54504 Vandaeuvre Nancy, France. fabrice.lemoine@ensem.inpl-nancy.fr ABRAMZON B, 1989, INT J HEAT MASS TRAN, V32, P1605, DOI 10.1016/0017-9310(89)90043-4; Castanet G, 2005, EXP FLUIDS, V39, P431, DOI 10.1007/s00348-005-0931-6; Castanet G, 2005, INT J HEAT MASS TRAN, V48, P3261, DOI 10.1016/j.ijheatmasstransfer.2005.03.005; Castanet G, 2005, COMBUST SCI TECHNOL, V177, P2395, DOI 10.1080/00102200500241206; Castanet G, 2003, EXP FLUIDS, V35, P563, DOI 10.1007/s00348-003-0702-1; CHIANG CH, 1992, INT J HEAT MASS TRAN, V35, P1307, DOI 10.1016/0017-9310(92)90186-V; CHIANG CH, 1993, INT J HEAT MASS TRAN, V36, P875, DOI 10.1016/S0017-9310(05)80271-6; Clift R., 1978, BUBBLES DROPS PARTIC; ELPERIN T, 1995, INT J HEAT MASS TRAN, V38, P409, DOI 10.1016/0017-9310(94)00168-U; HUBBARD GL, 1975, INT J HEAT MASS TRAN, V18, P1003, DOI 10.1016/0017-9310(75)90217-3; Lavieille P, 2000, EXP FLUIDS, V29, P429, DOI 10.1007/s003480000109; Lavieille P, 2001, EXP FLUIDS, V31, P45, DOI 10.1007/s003480000257; Sirignano W.A., 1999, FLUID DYNAMICS TRANS, DOI 10.1017/CBO9780511529566; Virepinte JF, 2000, COMBUST SCI TECHNOL, V150, P143, DOI 10.1080/00102200008952121 14 9 10 1 9 ELSEVIER SCIENCE INC NEW YORK STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA 1540-7489 1873-2704 P COMBUST INST Proc. 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Inst. 2007 31 2 2141 2148 10.1016/j.proci.2006.07.043 http://dx.doi.org/10.1016/j.proci.2006.07.043 8 Thermodynamics; Energy & Fuels; Engineering, Chemical; Engineering, Mechanical Science Citation Index Expanded (SCI-EXPANDED) Thermodynamics; Energy & Fuels; Engineering 258HE Green Submitted 2024-02-26 WOS:000252858200052 J Castelán, F; Mulet, J; Aldea, M; Sala, S; Sala, F; Criado, M Castelan, Francisco; Mulet, Jose; Aldea, Marcos; Sala, Salvador; Sala, Francisco; Criado, Manuel Cytoplasmic regions adjacent to the M3 and M4 transmembrane segments influence expression and function of α7 nicotinic acetylcholine receptors.: A study with single amino acid mutants JOURNAL OF NEUROCHEMISTRY English Article cytoplasmic loop; expression; function; nicotinic; receptor 5-HYDROXYTRYPTAMINE TYPE-3; CHANNEL CONDUCTANCE; SUBUNIT; LOOP; TRAFFICKING; TRANSCRIPTION; DIVERSITY; PROTEIN; SIGNAL We studied the role of the cytoplasmic regions adjacent to the M3 and M4 transmembrane segments of alpha 7 nicotinic receptors in the expression of functional channels. For this purpose, a total of 50 amino acids were mutated throughout the mentioned regions. Mutants close to M3, from Arg294 to Leu321, showed slight modifications in the levels of alpha-bungarotoxin binding sites and acetylcholine-evoked currents. Exceptions were mutants located at two clusters (His296 to Pro300 and Ile312 to Trp316), which exhibited low expression levels. In addition, some mutants showed altered functional responses. Many mutants close to M4 showed increased receptor expression, especially the ones located at the hydrophobic face of a putative amphipathic helix. This effect seems to be the consequence of a combination of increased receptor biosynthesis, higher transport efficiency and delayed degradation, such that we postulate that elements in the amphipathic domain strongly influence receptor stability. Finally, some mutants in this region showed altered functional responses: elimination of positively charged residues (Arg424 and Arg426) increased currents, whereas the opposite was observed upon suppression of negatively charged ones (Glu430 and Glu432). These results suggest that the cytoplasmic regions close to M3 and M4 play important structural and functional roles. Univ Miguel Hernandez, CSIC, Inst Neurociencias Alicante, Alicante 03550, Spain Consejo Superior de Investigaciones Cientificas (CSIC); Universidad Miguel Hernandez de Elche; CSIC-UMH - Instituto de Neurociencias de Alicante (IN) Criado, M (corresponding author), Univ Miguel Hernandez, CSIC, Inst Neurociencias Alicante, Alicante 03550, Spain. manuel.criado@umh.es Criado, Manuel/K-5109-2014; Mulet, Jose/K-6538-2014; Castelan, Francisco/AFU-8435-2022; Aldea, Marcos/H-8154-2015; Sala, Salvador/L-7104-2014 Criado, Manuel/0000-0002-3953-0346; Mulet, Jose/0000-0001-7506-4875; Castelan, Francisco/0000-0002-9835-3335; Aldea, Marcos/0000-0003-2146-2733; Sala, Francisco/0000-0002-2080-7683; Sala, Salvador/0000-0002-5607-0097 Alkondon M, 2004, PROG BRAIN RES, V145, P109, DOI 10.1016/S0079-6123(03)45007-3; Berg DK, 2002, J NEUROBIOL, V53, P512, DOI 10.1002/neu.10116; Boyd GW, 2003, J BIOL CHEM, V278, P27681, DOI 10.1074/jbc.M304938200; Bray C, 2005, MOL HUM REPROD, V11, P881, DOI 10.1093/molehr/gah245; Castillo M, 2005, J BIOL CHEM, V280, P27062, DOI 10.1074/jbc.M503746200; Christianson JC, 2004, EMBO J, V23, P4156, DOI 10.1038/sj.emboj.7600436; Colquhoun D, 2004, TRENDS NEUROSCI, V27, P337, DOI 10.1016/j.tins.2004.04.010; Devillers-Thiéry A, 2003, BIOL CELL, V95, P373, DOI 10.1016/S0248-4900(03)00084-4; DEVREOTES PN, 1975, J CELL BIOL, V65, P335, DOI 10.1083/jcb.65.2.335; FINERMOORE J, 1984, P NATL ACAD SCI-BIOL, V81, P155, DOI 10.1073/pnas.81.1.155; GARCIAGUZMAN M, 1994, BIOCHEMISTRY-US, V33, P15198, DOI 10.1021/bi00254a031; Hales TG, 2006, J BIOL CHEM, V281, P8062, DOI 10.1074/jbc.M513222200; Karlin A, 2002, NAT REV NEUROSCI, V3, P102, DOI 10.1038/nrn731; Kelley SP, 2003, NATURE, V424, P321, DOI 10.1038/nature01788; KRIEG PA, 1984, NUCLEIC ACIDS RES, V12, P7057, DOI 10.1093/nar/12.18.7057; Kuo YP, 2005, J PHARMACOL EXP THER, V314, P455, DOI 10.1124/jpet.105.084954; Le Novère N, 1999, BIOPHYS J, V76, P2329, DOI 10.1016/S0006-3495(99)77390-X; Le Novère N, 2002, J NEUROBIOL, V53, P447, DOI 10.1002/neu.10153; Li XW, 2006, LIFE SCI, V78, P1863, DOI 10.1016/j.lfs.2005.08.031; Margeta-Mitrovic M, 2000, NEURON, V27, P97, DOI 10.1016/S0896-6273(00)00012-X; Millar NS, 2003, BIOCHEM SOC T, V31, P869, DOI 10.1042/BST0310869; Reynolds PR, 2005, J BIOL CHEM, V280, P32548, DOI 10.1074/jbc.M502231200; Sanders T, 2004, J BIOL CHEM, V279, P51460, DOI 10.1074/jbc.M409533200; Sine SM, 2006, NATURE, V440, P448, DOI 10.1038/nature04708; Unwin N, 2005, J MOL BIOL, V346, P967, DOI 10.1016/j.jmb.2004.12.031; Valor LM, 2002, BIOCHEMISTRY-US, V41, P7931, DOI 10.1021/bi025831r; Wanamaker CP, 2003, ANN NY ACAD SCI, V998, P66, DOI 10.1196/annals.1254.009; Weibezahn J, 2005, BIOL CHEM, V386, P739, DOI 10.1515/BC.2005.086; Zerangue N, 1999, NEURON, V22, P537, DOI 10.1016/S0896-6273(00)80708-4 29 15 19 0 4 BLACKWELL PUBLISHING OXFORD 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND 0022-3042 J NEUROCHEM J. Neurochem. JAN 2007 100 2 406 415 10.1111/j.1471-4159.2006.04202.x http://dx.doi.org/10.1111/j.1471-4159.2006.04202.x 10 Biochemistry & Molecular Biology; Neurosciences Science Citation Index Expanded (SCI-EXPANDED) Biochemistry & Molecular Biology; Neurosciences & Neurology 119DV 17076762 2024-02-26 WOS:000242993300012 J Castelán-Ortega, OA; Estrada-Flores, JG; Smith, DG; Colunga, B; Solís-Méndez, A; Avilés-Nova, F; Ramirez, A; García, I Castelan-Ortega, O. A.; Estrada-Flores, J. G.; Smith, D. G.; Colunga, B.; Solis-Mendez, A.; Aviles-Nova, F.; Ramirez, A.; Garcia, I. Use of n-alkanes for estimation of voluntary intake and digestibility in donkeys (Equus asinus) JOURNAL OF ANIMAL AND FEED SCIENCES English Article donkey; n-alkanes; voluntary intake; digestibility The aim of this work was to evaluate if the n-alkanes (C32) technique can be used to determine voluntary dry matter intake (DMI) and dry matter digestibility (DMD) in grazing donkeys. Two experiments were carried out; in trial I DMI and DMD were measured using n-alkanes in four caged donkeys. In trial 2, n-alkanes were used to predict DMI and DMD in six donkeys grazing a star grass sward (Cynodon nlemfluensis). Results from both experiments suggest that the n-alkanes technique can be used to predict DMI and DMD with similar results than those obtained with other more sophisticated or expensive techniques. [Castelan-Ortega, O. A.; Estrada-Flores, J. G.; Colunga, B.; Solis-Mendez, A.; Ramirez, A.; Garcia, I.] Autonomous Univ State Mexico, Ctr Res Agr Sci, Literary Inst, Toluca 50000, Mexico; [Smith, D. G.] Univ Aberdeen, Dept Agr & Forestry, Aberdeen AB24 4FA, Scotland; [Aviles-Nova, F.] Autonomous Univ State Mexico, Temascaltepec Univ Ctr, Temascaltepec 5130, Mexico Universidad Autonoma del Estado de Mexico; University of Aberdeen; Universidad Autonoma del Estado de Mexico Castelán-Ortega, OA (corresponding author), Autonomous Univ State Mexico, Ctr Res Agr Sci, Literary Inst, Toluca 50000, Mexico. oaco@uaemex.mx Castelán-Ortega, Octavio Alonso/AAH-3604-2020 Ali HAM, 2004, J AGR SCI-CAMBRIDGE, V142, P71, DOI 10.1017/S0021859604004034; Brosh A, 2003, J AGR SCI, V140, P93, DOI 10.1017/S0021859602002757; Carretero-Roque L, 2005, TROP ANIM HEALTH PRO, V37, P123, DOI 10.1007/s11250-005-9012-3; Colunga GB, 2005, TROP ANIM HEALTH PRO, V37, P143, DOI 10.1007/s11250-005-9013-2; Crozier JA, 1997, J ANIM SCI, V75, P1651; DOVE H, 2003, SAT M 6 INT S NUTR H; GUDMUNDSSON O, 1998, TECHIQUES INVESTIGAT; Mayes R. W., 1988, Proceedings of the 12th General Meeting of the European Grassland Federation, Dublin, Ireland, July 4-7, 1988., P159; Mayes RW, 2000, NUTR RES REV, V13, P107, DOI 10.1079/095442200108729025; Ordakowski AL, 2001, J ANIM SCI, V79, P1516; Smith DG, 2007, J AGR SCI, V145, P273, DOI 10.1017/S0021859607006788 11 4 5 0 3 KIELANOWSKI INST ANIMAL PHYSIOLOGY NUTRITION JABLONNA UL INSTYTUCKA 3, 05-110 JABLONNA, POLAND 1230-1388 J ANIM FEED SCI J. Anim. Feed Sci. 2007 16 2 307 312 10.22358/jafs/74513/2007 http://dx.doi.org/10.22358/jafs/74513/2007 6 Agriculture, Dairy & Animal Science Science Citation Index Expanded (SCI-EXPANDED) Agriculture V13BH Green Submitted, hybrid 2024-02-26 WOS:000207641800052 J Castelle, B; Turner, IL; Ruessink, BG; Tomlinson, RB Castelle, B.; Turner, I. L.; Ruessink, B. G.; Tomlinson, R. B. Impact of storms on beach erosion: Broadbeach (Gold Coast, Australia) JOURNAL OF COASTAL RESEARCH English Article Subaerial beach; intermediate beach; video imagery; wave buoy The 70 km long Queensland Gold Coast has been one of Australia's premier coastal holiday resort destinations for more than 40 years. Extreme events, particularly tropical cyclones approaching the area, can generate storm waves and surges which have caused widespread episodic damage to the local economy. Broadbeach, located on the Gold Coast, is a double-barred beach which is representative of most of the Gold Coast beaches. The present study aims to quantify Broadbeach response to storm events in order to assess the ability of this beach to withstand extreme events and to recover during periods of lower wave energy. From the 1(st) of March to the 10(th) of July, 2006, 35 accurate subaerial beach surveys were undertaken. ARGUS images were used to estimate the location of the nearshore bars. During this period, Broadbeach experienced three storm erosion events. Offshore buoy measurements are used to estimate wave conditions that occurred. The first storm (from the 2(nd) to the 6(th) of March) was a hybrid-cyclone which generated one of the most energetic wave conditions on the Gold Coast of the past 30 years, with measured offshore significant wave height reaching 5.3 m, and maximum wave height 10.7 m at the Gold Coast Seaway buoy. During the two other storm wave events, wave conditions were much less energetic than during the first storm, with significant wave heights ranging from 2 to 3 m. The early March extreme event resulted in a 48m(3)/m erosion of the subaerial beach and a 70 m seaward migration of the outer bar in just a few days. Abnormally high erosion rates were measured during both the second and third storm wave events. This may be explained by the outer bar decay following the early March extreme event, which did not provide any significant protection during the subsequent two storm wave events. The severe erosion measured in this study suggests that the current average beach width may be too narrow to withstand an extreme event succession similar to the conditions that occurred in 1967. [Castelle, B.; Tomlinson, R. B.] Griffith Univ, Griffith Ctr Coastal Management, Griffith, NSW 9726, Australia; [Turner, I. L.] Univ New S Wales, Sch Civil & Environm Engn, Water Res Lab, Sydney, NSW 2093, Australia; [Ruessink, B. G.] Univ Utrecht, Inst Marine & Atmospher Res, Fac Geosci, Utrecht, Netherlands Griffith University; University of New South Wales Sydney; Utrecht University Castelle, B (corresponding author), Griffith Univ, Griffith Ctr Coastal Management, Griffith, NSW 9726, Australia. b.castelle@griffith.edu.au; ian.turner@unsw.edu.au; g.ruessink@geo.uu.nl; r.tomlinson@griffith.edu.au Tomlinson, Rodger B/C-2629-2009; Turner, Ian L/H-7122-2014; Castelle, Bruno/AAD-3962-2020 Turner, Ian L/0000-0001-9884-6917; Castelle, Bruno/0000-0003-1740-7395; Ruessink, Gerben/0000-0001-9526-6087 AGSO, 2001, AGSO GEOSC AUSTR, P389; Allen M., 1999, EXTREME WAVE CONDITI; Boak EH, 2005, J COASTAL RES, V21, P688, DOI 10.2112/03-0071.1; CASTELLE B., 2006, P 15 NSW COAST C COF; Castelle B, 2007, COAST ENG, V54, P77, DOI 10.1016/j.coastaleng.2006.08.007; Dail HJ, 2000, MAR GEOL, V162, P443, DOI 10.1016/S0025-3227(99)00072-9; DHL, 1970, R257 DELFT HYDR LAB; Dyson A., 2001, Proc. 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Res. 2007 50 534 539 6 Environmental Sciences; Geography, Physical; Geosciences, Multidisciplinary Science Citation Index Expanded (SCI-EXPANDED) Environmental Sciences & Ecology; Physical Geography; Geology V16HI 2024-02-26 WOS:000207860300102 J Castelo-Branco, G; Falcao, AM; Hermanson, O Castelo-Branco, Goncalo; Falcao, Ana Mendanha; Hermanson, Ola Epigenetic regulation of oligodendrocyte development by histone deacetylases NEURON GLIA BIOLOGY English Meeting Abstract [Castelo-Branco, Goncalo; Falcao, Ana Mendanha; Hermanson, Ola] Karolinska Inst, S-17177 Stockholm, Sweden Karolinska Institutet Castelo-Branco, Gonçalo/B-1635-2009; , Ola/AAF-5126-2021 0 0 0 0 0 CAMBRIDGE UNIV PRESS NEW YORK 32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA 1740-925X NEURON GLIA BIOL Neuron Glia Biol. 2007 2 1 S41 S41 1 Neurosciences Science Citation Index Expanded (SCI-EXPANDED) Neurosciences & Neurology 242FB 2024-02-26 WOS:000251708800122 J Castillo, D; Astudillo, P; Mares, J; González, FJ; Vela, A; Tiburcio, J Castillo, Dolores; Astudillo, Pablo; Mares, Jennifer; Gonzalez, Felipe J.; Vela, Alberto; Tiburcio, Jorge Chemically controlled self-assembly of [2]pseudorotaxanes based on 1,2-bis(benzimidazolium) ethane cations and 24-crown-8 macrocycles ORGANIC & BIOMOLECULAR CHEMISTRY English Article ORGANIC ROTAXANE FRAMEWORKS; CROWN-ETHER WHEELS; 1,2-BIS(PYRIDINIUM)ETHANE AXLES; INTERLOCKED MOLECULES; BIS-BENZIMIDAZOLES; POLYROTAXANES; TEMPLATE; MUSCLES; MOTIF; DIBENZO-24-CROWN-8 Cations derived from 1,2-bis(benzimidazolium)ethane can penetrate the cavity of dibenzo-24-crown-8 macrocycles to produce a new family of [2]pseudorotaxanes. These supramolecular structures are held together by a series of charge-assisted hydrogen bonds (+)N-H center dot center dot center dot O, ion-dipole and pi-stacking interactions. These new adducts were fully characterised by NMR spectroscopy, ESI mass spectrometry and single-crystal X-ray diffraction. The effect of electron-donating and electron-withdrawing groups on the association constants was also analyzed. Chemical control of the threading/unthreading process was achieved by the alternate addition of acid and base. 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J. Clin. Microbiol. Infect. Dis. JAN 2007 26 1 77 78 10.1007/s10096-006-0242-8 http://dx.doi.org/10.1007/s10096-006-0242-8 2 Infectious Diseases; Microbiology Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S) Infectious Diseases; Microbiology 135UL 17180346 2024-02-26 WOS:000244179300012 J Castillo, I; Calvo, MV; Alonso, L; Juárez, M; Fontecha, J Castillo, I.; Calvo, M. V.; Alonso, L.; Juarez, M.; Fontecha, J. Changes in lipolysis and volatile fraction of a goat cheese manufactured employing a hygienized rennet paste and a defined strain starter FOOD CHEMISTRY English Article Rennet paste; goat cheese flavor; lipolysis; volatile fraction SUBSP CASEI IFPL731; EWES MILK CHEESES; SENSORY CHARACTERISTICS; FLAVOR COMPOUNDS; FATTY-ACIDS; GAS-CHROMATOGRAPHY; LACTOCOCCUS-LACTIS; DYNAMIC HEADSPACE; MANCHEGO CHEESE; CHEDDAR CHEESE The effect of a hygienized rennet paste (HRP) and a defined strain starter IFPL on the volatile fraction of goat cheese (Majorero) was examined. Three batches were made and those cheeses produced either industrially (IL) or in artisanal manner (AL) were compared with the experimental lot (EL), which included both HRP and IFPL starter in its manufacture. Analysis of the volatile fraction was by static headspace connected to GC-MS and this disclosed a total of 28 components belonging to the following chemical families: fatty acids, esters, ketones, aldehydes and alcohols. Most of the volatile components identified appeared in all lots but at different concentrations. IL cheeses were distinguished from the other lots, including HRP in their manufacture, essentially by a lower presence of esters and FFA (both branched-chain and aliphatic acids). The use of HRP and a defined strain starter culture (including Lb. casei IFPL 731 as adjunct) directly affected lipolysis degree. This was reflected in an increase in the mono-and diglyceride concentrations and in a greater content of short-chain FFA, particularly butanoic acid, an important flavour component, which imparts a desirable sharp, piquant" taste to Majorero cheese. The IFPL starter culture also had a significant effect on concentrations of compounds such as 2-methyl-l-propanol, 3 methyl-l-butanol, isoamyl butyrate and acetoin. (c) 2005 Elsevier Ltd. All rights reserved.