Biological Stimulation of the Human Skin Applying Health-Promoting Light and Plasma Sources

被引：36

作者：

Awakowicz, P. ^{[1
]}

Bibinov, N. ^{[1
]}

Born, M. ^{[8
]}

Busse, B. ^{[10
]}

Gesche, R. ^{[5
]}

Helmke, A. ^{[9
]}

Kaemling, A. ^{[3
]}

Kolb-Bachofen, V. ^{[6
]}

Kovacs, R. ^{[2
]}

Kuehn, S. ^{[5
]}

Liebmann, J. ^{[6
]}

Mertens, N. ^{[9
]}

Niemann, U. ^{[8
]}

Oplaender, C. ^{[4
]}

Porteanu, H. -E. ^{[5
]}

Scherer, J. ^{[2
]}

Suschek, C. ^{[4
]}

Vioel, W. ^{[7
,9
]}

Wandke, D. ^{[3
]}

机构：

[1] Ruhr Univ Bochum, Ctr Plasma Sci & Technol, Bochum, Germany

[2] Aurion Anlagentech GmbH, Seligenstadt, Germany

[3] CINOGY GmbH, Duderstadt, Germany

[4] Univ Clin, Clin Plast Surg, Aachen, Germany

[5] Ferdinand Braun Inst Hoechstfrequenztech, Berlin, Germany

[6] Univ Dusseldorf, Inst Immunobiol, Dusseldorf, Germany

[7] Laser Lab, Gottingen, Germany

[8] Philips Res, Aachen, Germany

[9] Univ Appl Sci & Arts, Gottingen, Germany

[10] Zell Kontakt GmbH, Noerten Hardenberg, Germany

来源：

CONTRIBUTIONS TO PLASMA PHYSICS | 2009年 / 49卷 / 09期

关键词：

Dielectric barrier discharge; plasma medicine; plasma treatment; atmospheric pressure plasma; plasma source; microwave; microplasma; nitrogen monoxide; light source; cell-proliferation; skin disease; algorithms; medical treatment;

D O I：

10.1002/ctpp.200910068

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

In the frame of BMBF project "BioLiP", new physical treatment techniques aiming at medical treatment of the human skin have been developed. The acronym BioLiP stands for "Desinfektion, Entkeimung und biologische Stimulation der Haut durch gesundheitsfordernde Licht- und Plasmaquellen" (Disinfection, germ reduction and biological stimulation of the human skin by health promoting light and plasma sources). A source applying a low-temperature dielectric barrier discharge plasma (DBD) has been investigated on its effectiveness for skin disinfection and stimulation of biological material. Alternatively an atmospheric plasma source consisting of a microwave resonator combined with a solid state power oscillator has been examined. This concept which allows for a compact and efficient design avoiding external microwave power supply and matching units has been optimized with respect to nitrogen monoxide (NO) production in high yields. In both cases various application possibilities in the medical and biological domain are opened Lip, Light sources in the visible spectral range have been investigated with respect to the proliferation of human cell types. Intensive highly selective blue light sources based on LED technology can slow down proliferation rates without inducing toxic effects which offers new opportunities for treatments of so-called hyperproliferative skin conditions (e.g. with psoriasis or in Wound healing) using UV-frec light. (C) 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：641 / 647

页数：7

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