A WNT7B-m6A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis

被引：24
作者：
Gao, Qian [1 ,2 ]
Yang, Liuyang [1 ,2 ,3 ]
Shen, Aolin [3 ,4 ]
Li, Yang [2 ]
Li, Yongxiang [4 ]
Hu, Shilian [1 ,3 ]
Yang, Runhuai [5 ]
Wang, Xiangting [1 ]
Yao, Xuebiao [6 ]
Shen, Guodong [1 ,3 ]
机构：
[1] Univ Sci & Technol China, Affiliated Hosp USTC 1, Div Life Sci & Med, Dept Geriatr, Hefei 230001, Anhui, Peoples R China
[2] Anhui Med Univ, Sch Life Sci, Dept Genet, Hefei 230032, Anhui, Peoples R China
[3] Anhui Prov Key Lab Tumor Immunotherapy & Nutr The, Hefei 230001, Anhui, Peoples R China
[4] Anhui Med Univ, Dept Gen Surg, Affiliated Hosp 1, Hefei 230022, Anhui, Peoples R China
[5] Anhui Med Univ, Sch Biomed Engn, Hefei 230032, Anhui, Peoples R China
[6] Univ Sci & Technol China, MOE Key Lab Membrane Less Organelles & Cellular D, Hefei 230027, Anhui, Peoples R China
来源：
SIGNAL TRANSDUCTION AND TARGETED THERAPY | 2021年 / 6卷 / 01期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1038/s41392-020-00397-z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：3
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共 5 条
[1]   Regulation of Gene Expression by N6-methyladenosine in Cancer [J].
Liu, Jun ;
Harada, Bryan T. ;
He, Chuan .
TRENDS IN CELL BIOLOGY, 2019, 29 (06) :487-499
[2]   Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities [J].
Nusse, Roel ;
Clevers, Hans .
CELL, 2017, 169 (06) :985-999
[3]   METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance [J].
Wang, Qiang ;
Chen, Chen ;
Ding, Qingqing ;
Zhao, Yan ;
Wang, Zhangding ;
Chen, Junjie ;
Jiang, Zerun ;
Zhang, Yan ;
Xu, Guifang ;
Zhang, Jingjing ;
Zhou, Jianwei ;
Sun, Beicheng ;
Zou, Xiaoping ;
Wang, Shouyu .
GUT, 2020, 69 (07) :1193-1205
[4]   METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway [J].
Yang, Dong-Dong ;
Chen, Zhan-Hong ;
Yu, Kai ;
Lu, Jia-Huan ;
Wu, Qi-Nian ;
Wang, Yun ;
Ju, Huai-Qiang ;
Xu, Rui-Hua ;
Liu, Ze-Xian ;
Zeng, Zhao-Lei .
FRONTIERS IN ONCOLOGY, 2020, 10
[5]   LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway [J].
Yang, Xian-Zi ;
Cheng, Tian-Tian ;
He, Qing-Jun ;
Lei, Zi-Ying ;
Chi, Jun ;
Tang, Zhen ;
Liao, Quan-Xing ;
Zhang, Hong ;
Zeng, Li-Si ;
Cui, Shu-Zhong .
MOLECULAR CANCER, 2018, 17
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