Glutamatergic neurotransmission in the nucleus tractus solitarii: Structural and functional characteristics

被引：27

作者：

Baude, Agnes ^{[1
]}

Strube, Caroline ^{[1
]}

Tell, Fabien ^{[1
]}

Kessler, Jean-Pierre ^{[1
]}

机构：

[1] Univ Aix Marseille 2, Ctr Rech Neurobiol Neurophysiol Marseille, UMR 6231, CNRS,Univ Paul Cezanne, Marseille, France

来源：

JOURNAL OF CHEMICAL NEUROANATOMY | 2009年 / 38卷 / 03期

关键词：

Vesicular glutamate transporters; AMPA receptors; NMDA receptors; Metabotropic receptors; Synaptic plasticity; Synaptogenesis; METHYL-D-ASPARTATE; AMPA RECEPTOR SUBUNITS; LONG-TERM POTENTIATION; AFFERENT SYNAPTIC TRANSMISSION; PRIMARY GUSTATORY NUCLEUS; NITRIC-OXIDE SYNTHASE; AUTONOMIC CELL GROUPS; DORSAL VAGAL COMPLEX; RAT MEDIAL NUCLEUS; BRAIN-STEM NUCLEI;

D O I：

10.1016/j.jchemneu.2009.03.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glutamate is the main excitatory transmitter in the central nervous system. As such, it plays a major role in transmitting and processing visceral sensory information within the nucleus tractus solitarii (NTS). Here, we review current knowledge on NTS glutamatergic transmission. We describe the main organizational features of NTS glutamatergic synapses as determined by work performed during the last decade using antibodies against glutamate receptors and transporters proteins. In light of these recent neuronatomical findings, we discuss some functional properties of developing and adult NTS glutamatergic synapses. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：145 / 153

页数：9

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