In vivo activities of Baicalin against Chlamydia trachomatis

被引：0
作者：
Qi Xiaojuan [1 ,2 ]
Iei, Fu [1 ]
Wen, Su [1 ]
Yi Yandong [1 ]
Hao, Huang [1 ]
机构：
[1] Wuhan First Hosp, Ctr Med Expt, Wuhan 430022, Peoples R China
[2] Maternal & Child Care Serv Ctr Wuhans Qingshan Di, Wuhan 430022, Peoples R China
来源：
AFRICAN JOURNAL OF BIOTECHNOLOGY | 2010年 / 9卷 / 11期
关键词：
Chlamydia trachomatis; Baicalin; vaginally infected; INFECTION; CELLS;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Our previous studies have shown that Baicalin could effectively inhibit Chlamydia trachomatis in vitro. In this study, Baicalin was tested for potential antichlamydial activity using a murine genital Chlamydia trachomatis infection model. It was demonstrated that Baicalin significantly reduced C. trachomatis loading in BALB/c mice that were vaginally infected with the pathogen. On the basis of these data and our previous observations, we concluded that further evaluation of Baicalin for prevention and treatment of sexually transmitted chlamydial infection is warranted.
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页码：1663 / 1664
页数：2
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