Fibrosis and Cancer: Partners in Crime or Opposing Forces?

被引：39

作者：

Cox, Thomas R. ^{[1
]}

Erler, Janine T. ^{[1
]}

机构：

[1] Univ Copenhagen UCPH, BRIC, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark

来源：

TRENDS IN CANCER | 2016年 / 2卷 / 06期

关键词：

D O I：

10.1016/j.trecan.2016.05.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relation between fibrosis and cancer has long been debated, specifically whether desmoplasia precedes, accompanies, or succeeds tumourigenesis, progression, and metastasis. Recent reports have published opposing data, adding to the perplexity. However, what is emerging is that it is likely the specific properties of the extracellular matrix (ECM) that determine the paradoxical nature of cancer-associated fibrosis.

引用

页码：279 / 282

页数：5

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