Gold(I)-Catalyzed Enantioselective [4+2]-Cycloaddition of Allene-dienes

被引：140

作者：

Gonzalez, Ana Z. ^{[1
]}

Toste, F. Dean ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 01期

关键词：

DIALKYLZINC REAGENTS; CONJUGATE ADDITION; RING EXPANSION; GOLD CATALYSIS; CYCLOADDITIONS; COMPLEXES; ENYNES; HYDROAMINATION; HYDROARYLATION; CYCLIZATION;

D O I：

10.1021/ol902622b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective gold(I)-catalyzed Intramolecular [4 + 2]-cycloaddition of allenes and dienes is reported. The reactions allow for the asymmetric synthesis of trans-hexahydroindenes and pyrrolidine products using C-3-symmetric phosphitegold(I) and ortho-arylphosphoramiditegold(I) complexes as catalysts, respectively.

引用

页码：200 / 203

页数：4

共 41 条

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