Why aren't foamy viruses pathogenic?

被引：103

作者：

Linial, M ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98019 USA

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 06期

关键词：

D O I：

10.1016/S0966-842X(00)01763-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Foamy viruses are complex retroviruses that lead to either highly cytopathic or persistent infections in vitro, but to nonpathogenic lifelong infections in naturally or accidentally infected hosts. Factors that could contribute to these benign persistent infections include regulated transcription from the two viral promoters, the functions of the Bet accessory protein and the host immune response.

引用

页码：284 / 289

页数：6

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