Exploring the multifocal therapeutic approaches in COVID-19: A ray of hope

被引:3
作者
Kumar, Arun [1 ]
Dey, Asmita Deka [1 ]
Behl, Tapan [1 ]
Chadha, Swati [1 ]
Aggarwal, Vishal [1 ]
机构
[1] Chitkara Univ, Chitkara Coll Pharm, Chandigarh, Punjab, India
关键词
COVID-19; Effective therapies; Vaccines; Safety; Radiotherapy; CONVALESCENT PLASMA THERAPY; ACUTE RESPIRATORY SYNDROME; CORONAVIRUS SPIKE PROTEIN; ACUTE LUNG INJURY; GLUCOSE-METABOLISM; EXPRESSION; ANTIBODIES; BINDING; SAFETY; MODEL;
D O I
10.1016/j.intimp.2020.107156
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The ongoing global pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is marked as one of the most challenging infectious diseases in the history of mankind with affliction of similar to 29,737,453 confirmed cases globally. Looking at the present scenario where there is a parallel increment in curve with time, there is an utmost emergency to discover a perennial solution to this life-threatening virus which has led the Human race in an unusual state of affair. The entire health care fraternity is engaged in endeavouring an ultimate way out to hit this pandemic but no such research made till now has been approved yet, to have the potential to bring an end to this fatal situation. Although a few possible treatment choices exist at the moment yet the requirement to search for a still better therapeutic option remains persistent. Global laboratories are working day and night in search for an effective vaccine, many are undergoing clinical trials but their commercialization is no less than a year away. The present review highlights the current potential therapies viz., vaccines, immunotherapies, convulsant plasma therapies, corticosteroids, antithrombotic, intravenous immunoglobulins, nocturnal oxygen therapy etc. that may prove beneficial in attenuating the pandemic situation. However, comparison and presentation of collective data on the therapeutic advancements in mitigating the pandemic situation needs further clinical investigations in order to prove boon to mankind.
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页数:16
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