Sesterterpenes and a New Sterol from the Marine Sponge Phyllospongia foliascens

被引:13
作者
Zhang, Hong-Jun [1 ,2 ,3 ]
Yi, Yang-Hua [2 ]
Yang, Fan [1 ]
Chen, Wan-Sheng [1 ]
Lin, Hou-Wen [1 ]
机构
[1] Second Mil Med Univ, Changzheng Hosp, Dept Pharm, Lab Marine Drugs, Shanghai 200003, Peoples R China
[2] Second Mil Med Univ, Sch Pharm, Res Ctr Marine Drugs, Shanghai 200433, Peoples R China
[3] Hosp PLA Troops 95746, Qionglai 611531, Peoples R China
基金
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词
sesterterpene; sterol; marine sponge; Phyllospongia foliascens; SCALARANE-TYPE BISHOMOSESTERTERPENES; NATURAL-PRODUCTS; BISHOMOSCALARANE SESTERTERPENES; STREPSICHORDAIA-ALIENA; FOLIASPONGIN; PALLAS;
D O I
10.3390/molecules15020834
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new scalarane sesterterpene, phyllofolactone M (1), and a new sterol, (24E)-5 alpha,6 alpha-epoxystigmasta-7,24(28)-dien-3 beta-ol (3), together with a known sesterterpene, phyllofolactone B (2), were isolated from the South China Sea sponge Phyllospongia foliascens. Their structures were elucidated by spectroscopic analysis and comparison with known compounds. In addition, previous NMR data assignments for the known sesterterpene phyllofolactone B (2) were revised.
引用
收藏
页码:834 / 841
页数:8
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