Two New Metabolites, Epoxydine A and B, from Phoma sp.

被引:21
|
作者
Qin, Song [1 ]
Hussain, Hidayat [1 ]
Schulz, Barbara [2 ]
Draeger, Siegfried [2 ]
Krohn, Karsten [1 ]
机构
[1] Univ Gesamthsch Paderborn, Dept Chem, D-33098 Paderborn, Germany
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Mikrobiol, D-31806 Braunschweig, Germany
关键词
ACTIVE SECONDARY METABOLITES; ENDOPHYTIC FUNGI; NATURAL-PRODUCTS; MICROORGANISMS;
D O I
10.1002/hlca.200900199
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The new compounds, epoxydines A and B (1 and 2, resp.). along with the known and related metabolites, 3-6, were isolated from the fungal endophyte Phoma sp. The structures of the new compounds were elucidated by detailed spectroscopic analysis, and the relative configuration of I was confirmed by ROESY experiments. Preliminary studies indicated that compounds 2-5 possess good antibacterial, antifungal, and algicidal properties. Similarly, compound 1 showed antifungal and algicidal, and compound 6 antibacterial and algicidal properties.
引用
收藏
页码:169 / 174
页数:6
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