Preparation and characterization of a novel strontium-containing calcium phosphate cement with the two-step hydration process

被引：29
|
作者：
Yu, Tao [1 ]
Ye, Jiandong [1 ]
Wang, Yingjun [1 ]
机构：
[1] S China Univ Technol, Sch Mat Sci & Engn, Minist Educ, Key Lab Specially Funct Mat, Guangzhou 510641, Peoples R China
来源：
ACTA BIOMATERIALIA | 2009年 / 5卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Calcium phosphate cement; Strontium substitution; Hydration; Compressive strength; Radiopaque; MECHANOCHEMICAL-HYDROTHERMAL SYNTHESIS; BONE; HYDROXYAPATITE; RANELATE; BEHAVIOR; IONS;
D O I：
10.1016/j.actbio.2009.03.015
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A novel Sr-containing calcium phosphate cement (CPC) with excellent compressive strength, good radiopacity and suitable setting time was developed in this work. The two-step hydration reaction resulted in a high compressive strength, with a maximum of up to 74.9 MPa. Sr was doped into the calcium-deficient hydroxyapatite as a hydrated product during the hydration reaction of the CPC. Because of the existence of Sr element and the compact microstructure after hydration, the Sr-containing CPC shows good radiopacity. It is expected to be used in orthopedic and maxillofacial surgery for bone defects repairing. (C) 2009 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：2717 / 2727
页数：11
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