Nephrotic syndrome as paraneoplastic manifestation of a primary pulmonary lymphoepithelioma-like carcinoma

被引:0
作者
Arenas, M. D. [1 ]
Gil, M. T. [1 ]
Malek, T. [1 ]
Farre, J. [3 ]
Fernandez Morejon, F. J. [3 ]
Arriero, J. M. [4 ]
Aranda, I. [2 ]
Moledous, A. [1 ]
Alvarez-Ude, F. [5 ]
机构
[1] Hosp Perpetuo Socorro, Serv Nefrol, Alicante 03013, Spain
[2] Hosp Perpetuo Socorro, Serv Anat Patol, Alicante 03013, Spain
[3] Hosp San Jaime, Serv Anat Patol, Alicante, Spain
[4] Hosp San Juan de Alicante, Serv Neumol, Alicante, Spain
[5] H Gen Segovia, Serv Nefrol, Segovia, Spain
关键词
nephrotic syndrome; membranous glomerulonephritis; primary pulmonary lymphoepithelioma-like carcinoma; paraneoplastic syndrome; CELL LUNG-CANCER; MEMBRANOUS NEPHROPATHY; ASSOCIATION; PROGNOSIS; TUMOR;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
We present a case of nephrotic syndrome secondary to a membranous glomerulonephritis (MG), in a nonsmoking female with a solitary pulmonary nodule, which did not show growth during 2 years of follow-up. A biopsy by videothoracoscopy showed a granulomatous non-neoplastic process with giant multinucleated cells. The appearance of a nephrotic syndrome and its interpretation as paraneoplastic revealed the existence of a primary pulmonary lymphoepithelioma-like carcinoma (LELC), a very rare pulmonary tumor. After resection of tumor there was a complete recovery from the nephrotic syndrome. This case highlights how the investigation of paraneoplastic syndromes can help in the early diagnosis of some malignancies.
引用
收藏
页码:206 / 210
页数:5
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