Effects of piroxicam and meloxicam complexes of Co (II), Ni(II), Cu(II) and Zn(II) as inhibitors of cyclooxygenase-2 determined by Molecular docking

被引：0

作者：

Beteringhe, A. ^{[1
]}

机构：

[1] Romanian Acad, Inst Phys Chem, Lab Coordinat & Supramol Chem, Bucharest 060021, Romania

来源：

OPTOELECTRONICS AND ADVANCED MATERIALS-RAPID COMMUNICATIONS | 2015年 / 9卷 / 11-12期

关键词：

COX-2; Molecular Docking; Complexes; Piroxicam; Meloxicam; ANTIINFLAMMATORY DRUGS; SELECTIVE-INHIBITION; DISCOVERY; MECHANISM;

D O I：

暂无

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Was achieved a study involving Molecular docking method for selection of piroxicam and meloxicam complexes of Co (II), Ni(II), Cu(II) and Zn(II) as inhibitors of cyclooxygenase-2 (COX-2)center dot[Co(HMeI)(2)(H2O)(2)] - COX-2 complex with the lowest total energy (-1616.2 KJ/mol) was selected as a possible inhibitor of COX-2.

引用

页码：1527 / 1529

页数：3

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