Anti-TNF-α and hydralazine drug-induced lupus

被引：7

作者：

Quaresma, Maria Victoria ^{[1
]}

Bernardes Filho, Fred ^{[1
]}

de Oliveira, Fernanda Brandao ^{[1
]}

Pockstaller, Mercedes Prates ^{[1
]}

Reis Gavazzoni Dias, Maria Fernanda ^{[1
]}

Azulay, David Rubem ^{[1
]}

机构：

[1] Santa Casa da Misericordia Rio de Janeiro, Inst Dermatol Prof Rubem David Azulay, Rio De Janeiro, RJ, Brazil

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2015年 / 90卷 / 03期

关键词：

Acetyl-CoA C-Acetyltransferase; Acetylation; Autoimmunity; Hydralazine; Lupus erythematosus; cutaneous; Tumor necrosis factor-alpha;

D O I：

10.1590/abd1806-4841.20153893

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Drug-induced lupus is a rare drug reaction featuring the same symptoms as idiopathic lupus erythematosus. Recently, with the introduction of new medicines in clinical practice, an increase in the number of illnes-striggering implicated drugs has been reported, with special emphasis on anti-TNF-alpha drugs. In the up-to-date list, almost one hundred medications have been associated with the occurrence of drug-induced lupus. The authors present two case reports of the illness induced respectively by hydralazine and infliximab, addressing the clinical and laboratorial characteristics, diagnosis, and treatment.

引用

页码：125 / 129

页数：5

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