Pd/NHC-catalyzed cross-coupling reactions of nitroarenes

被引：54

作者：

Kashihara, Myuto ^{[1
]}

Zhong, Rong-Lin ^{[2
]}

Semba, Kazuhiko ^{[1
]}

Sakaki, Shigeyoshi ^{[2
]}

Nakao, Yoshiaki ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Mat Chem, Nishikyo Ku, Kyoto 6158510, Japan

[2] Kyoto Univ, Fukui Inst Fundamental Chem, Sakyo Ku, Kyoto 6068130, Japan

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 63期

关键词：

N-HETEROCYCLIC CARBENES; NUCLEOPHILIC DISPLACEMENT; DIRECT ARYLATION; BOND FORMATION; NITRO-GROUP; LIGANDS; DENITRATION; PHOSPHINE; REGIOSELECTIVITY; SUBSTITUTION;

D O I：

10.1039/c9cc05055h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Heterocyclic carbene (NHC) ligands effective for the cross-coupling of nitroarenes were identified. A rational design of the NHC ligand structures enabled significant reduction of catalyst loadings compared with the previous system employing BrettPhos as a phosphine ligand. Experimental and theoretical studies to compare these ligands gave some insights into high activity of the newly developed NHC ligands.

引用

页码：9291 / 9294

页数：4

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