Chemical Content and Biological Activity Spectrum of Nigella sativa Seed Oil

被引：13

作者：

Sicak, Yusuf ^{[1
]}

Erdogan Eliuz, Elif Ayse ^{[2
]}

机构：

[1] Mugla Sitki Kocman Univ, Koycegiz Vocat Sch, Dept Med & Aromat Plants, TR-48800 Mugla, Turkey

[2] Mersin Univ, Tech Sci Vocat Sch, Dept Food Technol, TR-33343 Mersin, Turkey

来源：

KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE | 2019年 / 22卷 / 06期

关键词：

Nigella sativa; Chemical Composition; Biological Activity; ANTIMICROBIAL ACTIVITY; VOLATILE OIL; ANTIOXIDANT; ACETYLCHOLINESTERASE; EXTRACTS;

D O I：

10.18016/ksutarimdoga.vi.537674

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

In this study, it was aimed to investigate the chemical composition and biological activities including antioxidant, anticholinesterase, antimicrobial and urease activity of Nigella sativa seed oil growing in Mugla (Koycegiz). The oil of plant was obtained using Soxhlet apparatus. Thirty-one components of the oil were determined by Gas Chromatography Mass Spectrometry (GC-MS). The major components of oil were detected as palmitic acid (10.48%), linoleic acid (8.05%), acyemene (7.11%), 3,5-dimethyl cyclohexanol (6.68%), thymoquinone (6.44%), p-tert-buthyl catechol (6.28%) and 8-methyl-1-undecene (3.28%). The findings obtained from biological activity assays showed that Nigella sativa oil was a promising candidate that can be used in the discovery of new drugs and the preparation of now natural drug preparations.

引用

页码：928 / 934

页数：7

共 50 条

[41] THE KINETICS OF HYDROLYSIS OF NIGELLA-SATIVA (BLACK CUMIN) SEED OIL CATALYZED BY NATIVE LIPASE IN GROUND SEED
DANDIK, L
AKSOY, HA
[J]. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1992, 69 (12) : 1239 - 1241
[42] Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed
Agbaria, Riad
Gabarin, Adi
Dahan, Arik
Ben-Shabat, Shimon
[J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 9 : 3119 - 3124
[43] In vitro Anti-atherothrombosis Activity of Nigella sativa Oil, Phytol and their Combinations
Islam, Muhammad Torequl
Molla, Shamim
Das, Apu Kumar
Zaman, Farhana
Khan, Md Roich
[J]. INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2019, 53 (04) : 670 - 674
[44] Cytotoxicity of Nigella Sativa Seed Oil and Extract Against Human Lung Cancer Cell Line
Al-Sheddi, Ebtesam Saad
Farshori, Nida Nayyar
Al-Oqail, Mai Mohammad
Musarrat, Javed
Al-Khedhairy, Abdulaziz Ali
Siddiqui, Maqsood Ahmed
[J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (02) : 983 - 987
[45] Nigella sativa seed-mediated green biosynthesis of silver nanoparticles and antimicrobial activity
Boke, E.
Saygi, K. Ozlem
Erenler, R.
Kacmaz, B.
Ergene, A.
[J]. REVISTA MEXICANA DE FISICA, 2024, 70 (05) : 1 - 7
[46] Antimicrobial and antioxidant activity of Nigella sativa Linn seeds
ul Islam, Shahid
Kamili, Azra N.
[J]. BIOSCIENCE BIOTECHNOLOGY RESEARCH COMMUNICATIONS, 2013, 6 (02): : 190 - 195
[47] Effect of Nigella sativa oil on experimental toxoplasmosis
Rasha F. Mady
Wessam El-Hadidy
Samar Elachy
[J]. Parasitology Research, 2016, 115 : 379 - 390
[48] Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection
Salem, ML
Hossain, MS
[J]. INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 2000, 22 (09): : 729 - 740
[49] Physicochemical, textural, and sensory characteristics of ice cream incorporated with Nigella sativa seed oil microcapsules
Makouie, Sina
Alizadeh, Mohammad
Khosrowshahi, Asghar
Maleki, Omid
[J]. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2021, 45 (10)
[50] The positive effect of black seed (Nigella sativa L.) essential oil on thyroid hormones in rats with hypothyroidism and hyperthyroidism
Avci, Gulcan
Ulutas, Elmas
Ozdemir, Vural
Kivrak, Ibrahim
Bulbul, Aziz
[J]. JOURNAL OF FOOD BIOCHEMISTRY, 2022, 46 (04)

← 1 2 3 4 5 →