Cytogenetic of myelodysplastic syndromes.

被引：0

作者：

Lai, JL ^{[1
]}

Fenaux, P ^{[1
]}

机构：

[1] CTR HOSP REG & UNIV LILLE,SERV MALAD SANG,F-59037 LILLE,FRANCE

来源：

PATHOLOGIE BIOLOGIE | 1997年 / 45卷 / 07期

关键词：

cytogenetic; myelodysplastic syndromes;

D O I：

暂无

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The authors review the main cytogenetic abnormalities encountered in MDS particularly del 5q, -7, +8, and complex abnormalities. Their presence may be useful to the diagnosis of MDS in difficult cases, Their prognostic value is important, and cytogenetics have recently been included in prognostic scores in MDS. Knowledge of recurrent chromosomal rearrangements is finally a first step in the discovery of genes implicated in the pathogenesis of MDS.

引用

页码：550 / 555

页数：6

共 26 条

[1]

ANDERSON JE, 1993, BLOOD, V82, P677

[2] PROPOSALS FOR THE CLASSIFICATION OF THE MYELODYSPLASTIC SYNDROMES [J].

BENNETT, JM ;

CATOVSKY, D ;

DANIEL, MT ;

FLANDRIN, G ;

GALTON, DAG ;

GRALNICK, HR ;

SULTAN, C .

BRITISH JOURNAL OF HAEMATOLOGY, 1982, 51 (02) :189-199

[3]

BOULTWOOD J, 1994, BLOOD, V84, P3253

[4] DENOVO MYELODYSPLASTIC SYNDROMES IN ADULTS AGED 50 OR LESS - A REPORT ON 37 CASES [J].

FENAUX, P ;

PREUDHOMME, C ;

ESTIENNE, MH ;

MOREL, P ;

LAL, JL ;

GARDIN, C ;

JOUET, JP ;

BAUTERS, F .

LEUKEMIA RESEARCH, 1990, 14 (11-12) :1053-1059

[5]

FENAUX P, 1991, BRIT J HAEMATOL, V77, P497

[6]

FLACTIF M, 1994, LEUKEMIA, V8, P1012

[7]

FONATSCH C, 1994, LEUKEMIA, V8, P1318

[8]

HEIM S, 1986, CLIN HAEMATOL, V15, P1003

[9] A PREDICTIVE MODEL FOR THE CLINICAL-RESPONSE TO LOW-DOSE ARA-C - A STUDY OF 102 PATIENTS WITH MYELODYSPLASTIC SYNDROMES OR ACUTE-LEUKEMIA [J].

HELLSTROMLINDBERG, E ;

ROBERT, KH ;

GAHRTON, G ;

LINDBERG, G ;

FORSBLOM, AM ;

KOCK, Y ;

OST, A .

BRITISH JOURNAL OF HAEMATOLOGY, 1992, 81 (04) :503-511

[10]

JENKINS RB, 1992, BLOOD, V79, P3307

← 1 2 3 →