Management of women with cervical cancer precursor lesions

There are a number of guiding principles that can be applied to the management of all women with cervical intraepithelial neoplasia (CIN), as well as for women not found to have CIN but who are likely to be at some continued risk due to the probability that the inability to document disease at colposcopy most likely reflects cellular changes secondary to human papillomavirus that may regress, persist, or progress. The management guidelines discussed in this article are either evidence-based or are based on expert opinion where the published literature is scant or inconclusive. Therefore, "guiding principles" are not based on definitive scientific validation yet may be helpful. These include proactive dietary measures aimed to improve the immune response and educational measures designed to reduce anxiety and empower the patient with a sense of control.