SIRS, Sepsis, CARS, ARDS: Understanding different aspects of the inflammatory response in intensive care patients

被引：0

作者：

Martinet, Olivier ^{[1
]}

Delabranche, Xavier ^{[1
,2
]}

Aghajanian, Majid ^{[1
]}

Hasselmann, Michel ^{[1
]}

机构：

[1] Hop Univ Strasbourg, Serv Reanimat Med, Nouvel Hop Civil, F-67091 Strasbourg, France

[2] Univ Strasbourg, Lab Biophoton & Pharmacol, Fac Pharm, CNRS,UMR 7213, F-67401 Illkirch Graffenstaden, France

来源：

NUTRITION CLINIQUE ET METABOLISME | 2009年 / 23卷 / 04期

关键词：

Inflammation; Sepsis; SIRS; Intensive care; Pharmaconutrition; Revue; ACUTE RESPIRATORY-DISTRESS; GAMMA-LINOLENIC ACID; POLYUNSATURATED FATTY-ACIDS; NECROSIS-FACTOR-ALPHA; EICOSAPENTAENOIC ACID; MEDICAL PROGRESS; WHOLE-BLOOD; OIL; ANTIOXIDANTS; EFFICACY;

D O I：

10.1016/j.nupar.2009.10.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Activation of the innate immune system is associated with an inflammatory reaction controlled by compensatory anti-inflammatory mechanisms. Failure of this control leads to a stereotyped clinical picture, SIRS and to severe organ dysfunctions such its septic shock and ARDS. Better understanding of the pathophysiological underlying mechanisms as provided opportunities to explore new ways of modulation of the inflammatory response. Unfortunately, results have been so far disappointing. A more precise selection of patients and of the timing of intervention may provide a greater efficacy of these treatments. Pharmaconutrition, by modifying cellular membranes lipid content and eicosanoids' production, offers all interesting alternative way. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：185 / 191

页数：7

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