Protein destruction by atmospheric pressure glow discharges

被引:151
作者
Deng, X. T.
Shi, J. J.
Chen, H. L.
Kong, M. G. [1 ]
机构
[1] Univ Loughborough, Dept Elect & Elect Engn, Loughborough LE11 3TU, Leics, England
[2] Univ Leicester, MRC, Toxicol Unit, Leicester LE1 9HN, Leics, England
关键词
D O I
10.1063/1.2410219
中图分类号
O59 [应用物理学];
学科分类号
摘要
It is well established that atmospheric pressure glow discharges are capable of bacterial inactivation. Much less known is their ability to destruct infectious proteins, even though surgical instruments are often contaminated by both bacteria and proteinaceous matters. In this letter, the authors present a study of protein destruction using a low-temperature atmospheric dielectric-barrier discharge jet. Clear evidences of protein removal are presented with data of several complimentary experiments using scanning electron microscopy, electron dispersive x-ray analysis, electrophoresis, laser-induced fluorescence microscopy, and protein reduction kinetics. Considerable degradation is observed of protein fragments that remain on their substrate surface after plasma treatment.
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页数:3
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共 21 条
[1]   Elimination of transmissible spongiform encephalopathy infectivity and decontamination of surgical instruments by using radio-frequency gas-plasma treatment [J].
Baxter, HC ;
Campbell, GA ;
Whittaker, AG ;
Jones, AC ;
Aitken, A ;
Simpson, AH ;
Casey, M ;
Bountiff, L ;
Gibbard, L ;
Baxter, RL .
JOURNAL OF GENERAL VIROLOGY, 2005, 86 :2393-2399
[2]   Iatrogenic Creutzfeldt-Jakob disease at the millennium [J].
Brown, P ;
Preece, M ;
Brandel, JP ;
Sato, T ;
McShane, L ;
Zerr, I ;
Fletcher, A ;
Will, RG ;
Pocchiari, M ;
Cashman, NR ;
d'Aignaux, JH ;
Cervenáková, L ;
Fradkin, J ;
Schonberger, LB ;
Collins, SJ .
NEUROLOGY, 2000, 55 (08) :1075-1081
[3]   Effects of microbial loading and sporulation temperature on atmospheric plasma inactivation of Bacillus subtilis spores -: art. no. 153901 [J].
Deng, XT ;
Shi, JJ ;
Shama, G ;
Kong, MG .
APPLIED PHYSICS LETTERS, 2005, 87 (15) :1-3
[4]   Physical mechanisms of inactivation of Bacillus subtilis spores using cold atmospheric plasmas [J].
Deng, Xutao ;
Shi, Jianjun ;
Kong, Michael G. .
IEEE TRANSACTIONS ON PLASMA SCIENCE, 2006, 34 (04) :1310-1316
[5]   Decontamination of chemical and biological warfare, (CBW) agents using an atmospheric pressure plasma jet (APPJ) [J].
Herrmann, HW ;
Henins, I ;
Park, J ;
Selwyn, GS .
PHYSICS OF PLASMAS, 1999, 6 (05) :2284-2289
[6]  
Hury S, 1998, LETT APPL MICROBIOL, V26, P417
[7]   Room temperature sterilization of surfaces and fabrics with a One Atmosphere Uniform Glow Discharge Plasma [J].
Kelly-Wintenberg, K ;
Montie, TC ;
Brickman, C ;
Roth, JR ;
Carr, AK ;
Sorge, K ;
Wadsworth, LC ;
Tsai, PPY .
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 1998, 20 (01) :69-74
[8]   Electrical and optical characterization of the plasma needle [J].
Kieft, IE ;
van der Laan, EP ;
Stoffels, E .
NEW JOURNAL OF PHYSICS, 2004, 6 :1-14
[9]  
KOVALEV VI, 2005, UNPUB 2 INT C OPT LA
[10]   BIOLOGICAL IMPACT OF SMALL AIR IONS [J].
KRUEGER, AP ;
REED, EJ .
SCIENCE, 1976, 193 (4259) :1209-1213